Evidence map›Paper›PMID 33614486›Full record

ReviewFrontiers in oncology2020

The Roles of circRNAs in Liver Cancer Immunity.

Ying Tang, Mei Jiang, Hai-Mei Jiang, Zeng Jie Ye, Yu-Sheng Huang, Xiu-Shen Li, Bin-Yu Qin, Rui-Sheng Zhou, Hua-Feng Pan, Da-Yong Zheng

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. CircRNA and miRNA expression analysis in livers of mice withFrontiers in cellular and infection microbiology · 2022
    Article
  12. Role of immune escape in different digestive tumours.World journal of clinical cases · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ying TangDepartment of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
Mei JiangDepartment of Oncology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Hai-Mei JiangDepartment of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zeng Jie YeDepartment of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yu-Sheng HuangDepartment of Oncology, Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiu-Shen LiDepartment of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
Bin-Yu QinDepartment of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
Rui-Sheng ZhouDepartment of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
Hua-Feng PanDepartment of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
Da-Yong ZhengDepartment of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are stable covalently closed non-coding RNAs (ncRNAs). Many studies indicate that circRNAs are involved in the pathological and physiological processes of liver cancer. However, the functions of circRNAs in liver cancer immunity are less known. In this review, we summarized the functions of circRNAs in liver cancer, including proliferative, metastasis and apoptosis, liver cancer stemness, cell cycle, immune evasion, glycolysis, angiogenesis, drug resistance/sensitizer, and senescence. Immune escape is considered to be one of the hallmarks of cancer development, and circRNA participates in the immune escape of liver cancer cells by regulating natural killer (NK) cell function. CircRNAs may provide new ideas for immunotherapy in liver cancer.

Indexed as

circRNAimmune evasioninnate immunityliver cancernatural killer (NK) cells

Identifiers

PMID33614486
PMCPMC7890029
OpenAlexW3127707775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.