Evidence map›Paper›PMID 33614317›Full record

ArticleCureus2021

Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?

Muhammad Faisal, Zubair Mumtaz, Abdul Mueed, Sajid Ali, Haseeb H Raza, Samra Khan, Sayeda Salma, Mustajab Mujtaba, Musa Karim, Faisal Qadir

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Muhammad FaisalElectrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Zubair MumtazElectrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Abdul MueedElectrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Sajid AliElectrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Haseeb H RazaElectrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Samra KhanMedicine, Liaquat National Hospital, Karachi, PAK.
Sayeda SalmaCardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Mustajab MujtabaCardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Musa KarimResearch, National Institute of Cardiovascular Diseases, Karachi, PAK.
Faisal QadirElectrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.
Liaquat National Hospital · PKNational Institute of Cardiovascular Diseases · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Hypothyroidism can be a cause of sinus bradycardia. However, thyroid laboratory evaluation is often performed routinely in patients with complete heart block (CHB) though there is little data to support this practice. This study aimed to assess the frequency of thyroid dysfunction in patients presenting with CHB without clinical features of hypothyroidism. Methodology All patients referred for permanent pacemaker implantation for CHB were included in this cross-sectional study. Patients with known thyroid disorder or clinical features of thyroid disorder were excluded. Demographic, electrocardiography (EKG), and routine thyroid stimulating hormone (TSH) screening results were recorded. Results A total of 102 patients with complete atrioventricular (AV) block were enrolled in the study of which 50.0% (51) were male. The mean age was 61.09 ± 11.74. Co-morbidities included diabetes mellitus 44.1% (45), smoking 36.3% (37), and hypertension 55.9% (57). Mean EKG atrial rate was 82.97 ± 31.31 mmHg with a mean ventricular escape rate of 36.17 ± 5.93. Permanent pacemakers were implanted in all of the patients. Only one patient had an abnormal TSH. Conclusions We found a very low prevalence of thyroid dysfunction among patients without clinical features of thyroid dysfunction presenting with third-degree AV block. This calls for cautious prescription of thyroid testing in clinically euthyroid patients.

Indexed as

atrioventricular blockcomplete heart blockpermanent pacemakersthyroid stimulating hormonetsh

Identifiers

PMID33614317
PMCPMC7883583
OpenAlexW3121126979

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.