ArticleACS sustainable chemistry & engineering2020
Expedient Organocatalytic Aza-Morita-Baylis-Hillman Reaction through Ball-Milling.
Article in ACS sustainable chemistry & engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Mechanochemistry for Organic and Inorganic Synthesis.ACS organic & inorganic Au · 2024Review
- Recent progress and prospects in the organocatalytic Morita-Baylis-Hillman reaction.RSC advances · 2024Review
- Mechanical Activation of Zero-Valent Metal Reductants for Nickel-Catalyzed Cross-Electrophile Coupling.ACS catalysis · 2022Article
- Mechanochemical Organocatalysis: Do High Enantioselectivities Contradict What We Might Expect?ChemSusChem · 2022Review
- Ball-Milling-Enabled Reactivity of Manganese Metal*.Angewandte Chemie (International ed. in English) · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A ball-milling enabled tertiary amine catalyzed aza-Morita-Baylis-Hillman reaction is reported. The reaction process does not require solvent, has significantly shorter reaction times than previous methods and is reported on a range of imines and acrylate Michael acceptors across than 26 examples. A 12-fold scaled-up example is also reported as well as experimental comparisons to solution-based experiments and neat-stirred reactions.
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Registered trials
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