Evidence map›Paper›PMID 33614195›Full record

ArticleACS catalysis2021

Rapid, Biomimetic Degradation of a Nerve Agent Simulant by Incorporating Imidazole Bases into a Metal-Organic Framework.

Hong-Bin Luo, Anthony J Castro, Megan C Wasson, Willmer Flores, Omar K Farha, Yangyang Liu

Open access · greenAbstract read
In one paragraph

Article in ACS catalysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 78 citations in OpenAlex.

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  13. Synthesis of a UiO-66/g-CRSC advances · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hong-Bin LuoDepartment of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, California 90032-8202, United States.ORCID 0000-0002-2225-7072
Anthony J CastroDepartment of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, California 90032-8202, United States.ORCID 0000-0003-0589-3170
Megan C WassonDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208-3113, United States.ORCID 0000-0002-9384-2033
Willmer FloresDepartment of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, California 90032-8202, United States.
Omar K FarhaDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208-3113, United States.ORCID 0000-0002-9904-9845
Yangyang LiuDepartment of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, California 90032-8202, United States.ORCID 0000-0002-3913-5979
California State University Los Angeles · USNorthwestern University · US

Funding

Research Initiative for Scientific Enhancement (RISE)R25GM061331 · NIGMS · CALIFORNIA STATE UNIVERSITY LOS ANGELES · PI FOSTER, KRISHNA L · 2000 to 2021
$33.1M
UNDERGRADUATE STUDENT TRAINING IN ACADEMIC RESEARCHT34GM008228 · NIGMS · CALIFORNIA STATE UNIVERSITY LOS ANGELES · PI TUNSTAD, LINDA M. · 1986 to 2022
$13.3M
TWO-YEAR TO FOUR-YEAR TRANSITION PROGRAMR25GM049001 · NIGMS · CALIFORNIA STATE UNIVERSITY LOS ANGELES · PI DINH, KIM-LIEN THI, MATHIAS, ERROL V · 1992 to 2022
$5.3M
Bridges to the Baccalaureate at Cal State LAT34GM150442 · NIGMS · CALIFORNIA STATE UNIVERSITY LOS ANGELES · PI Khuloud Sweimeh, LINDA M. TUNSTAD · 2023 to 2026
$967k
NIGMS NIH HHS R25 GM049001NIGMS NIH HHS R25 GM061331NIGMS NIH HHS T34 GM008228NIGMS NIH HHS T34 GM150442
6 · The paper itself

Abstract

Metal-organic frameworks (MOFs) are excellent catalytic materials for the hydrolytic degradation of nerve agents and their simulants. However, most of the MOF-based hydrolysis catalysts to date are reliant on liquid water media buffered by a volatile liquid base. To overcome this practical limitation, we developed a simple and feasible strategy to synthesize MOF composites that structurally mimic phosphotriesterase's active site as well as its ligated histidine residues. By incorporating imidazole and its derivative into the pores of

Indexed as

catalysismetal–organic frameworksnerve agentspure watersolid phase

Identifiers

PMID33614195
PMCPMC7889053
OpenAlexW3124100362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.