Evidence map›Paper›PMID 33614075›Full record

ArticleRoyal Society open science2021

Magnetic transfection with superparamagnetic chitosan-loaded IGFBP

Yue Tang, Jun Wu, Yuan Zhang, Lingpeng Ju, Xiangyang Qu, Dianming Jiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yue TangDepartment of Traumatic Joint Center, The Third Affiliated Hospital of Chongqing Medical University (General Hospital), No 1 Shuanghu Road, Yubei District, Chongqing 401120, People's Republic of China.ORCID 0000-0003-1470-3877
Jun WuDepartment of Orthopedics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Laboratory of Biomaterials, 136# Zhongshan 2 road, Yuzhong District, Chongqing 400014, People's Republic of China.
Yuan ZhangDepartment of Orthopedics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Laboratory of Biomaterials, 136# Zhongshan 2 road, Yuzhong District, Chongqing 400014, People's Republic of China.
Lingpeng JuDepartment of Orthopedics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Laboratory of Biomaterials, 136# Zhongshan 2 road, Yuzhong District, Chongqing 400014, People's Republic of China.
Xiangyang QuDepartment of Orthopedics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Laboratory of Biomaterials, 136# Zhongshan 2 road, Yuzhong District, Chongqing 400014, People's Republic of China.
Dianming JiangDepartment of Traumatic Joint Center, The Third Affiliated Hospital of Chongqing Medical University (General Hospital), No 1 Shuanghu Road, Yubei District, Chongqing 401120, People's Republic of China.ORCID 0000-0001-9935-7066
Children's Hospital of Chongqing Medical University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We prepared the superparamagnetic chitosan nanoparticles (SPCIONPs) to study the application of them as gene vectors using a magnetic transfection system for the targeted treatment of lung metastasis of osteosarcoma. The SPCIONPs were characterized by transmission electron microscopy, Fourier transform infrared spectrometry, superconducting quantum interference device and atomic force microscopy. Their biosafety was determined by cell counting kit-8 (CCK8) and live-dead staining assays. The transfection

Indexed as

biosafetyIGFBP5magnetic transfectionosteosarcomasuperparamagnetic chitosan iron oxide nanoparticles

Identifiers

PMID33614075
PMCPMC7890493
OpenAlexW3120423162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.