ReviewToxicology research2021
Comet assay: a versatile but complex tool in genotoxicity testing.
Review in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 161 citations in OpenAlex.
- The impact of physical exercise on genotoxicity in older adults: a systematic review.Biogerontology · 2025Pooled it
- Genotoxic and Physiological Responses to Repeated Exposure to Low-Concentration Silver Nanoparticles inInternational journal of molecular sciences · 2026Article
- Association of mitochondrial DNA haplogroup, oxidative DNA damage and inflammatory markers in middle-aged adults.International journal of radiation biology · 2026Article
- Impact of low-frequency electromagnetic fields on DNA instability caused by environmentally and occupationally relevant chemicals in lymphocytes of donors with different demographic characteristics.Archives of toxicology · 2026Article
- Trametes versicolor laccase induces apoptosis and DNA damage in colorectal cancer via reactive oxygen species-mediated signaling disruption.Molecular biology reports · 2026Article
- Genotoxic effects of association of the biogenic amines cadaverine and putrescine on the Xenopus tropicalis fibroblast cell line.Environmental science and pollution research international · 2026Article
- Dual-Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell-Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy.Advanced healthcare materials · 2026Article
- Targeting colorectal cancer with pyrazolo[4,3-e][1,2,4]triazine and pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides: comprehensive in vitro evaluation.Scientific reports · 2026Article
- Genotoxicity Assessment in Occupational Health Personnel Exposed to Cytostatic Drugs in a Peruvian Hospital.Genes · 2026Article
- A comparative genotoxicity study of agrochemicals: nuclear abnormalities, comet assay, and gene expression alterations.In vitro cellular & developmental biology. Animal · 2026Article
- Chemical Composition, Antioxidant Potential, and Genotoxic Safety of Lamiaceae Essential Oils from Eastern Morocco: A Multimethod Evaluation.Molecules (Basel, Switzerland) · 2026Article
- The Alkaline Comet Assay for Assessment of DNA Damage.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Phytochemical profiling and pharmacological evaluation ofFrontiers in pharmacology · 2026Article
- AI-based methods for the assessment of DNA damage and repair mechanisms.Frontiers in systems biology · 2026Review
- Assessment of the carcinogenic potential of automotive gasoline in humans based on mechanistic evidence.Current research in toxicology · 2026Article
- Cannabidiol does not cause DNA double-strand breaks in a human liver-derived cell model.Journal of cannabis research · 2025Article
- Agent-specific DNA repair kinetic in 3T3 cells: a comparative study using the in vitro comet assay.Toxicology research · 2025Article
- Utilization of the CometChip assay for detecting PAH-induced DNA bulky adducts in a 3D primary human bronchial epithelial cell model.Toxicology · 2025Article
- Comparative study between two types of Crocus sativus L. corms: chemical composition, antioxidant, genotoxic, and cytotoxic effects.Bioresources and bioprocessing · 2025Article
- Defining the parameters of comet assay for reliably detecting DNA damage as a marker of X-ray based irradiation in insects treated with non-lethal doses for export fruit sanitation.Pest management science · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It can also be applied to cells isolated from treated animals. In this review, we highlight advantages and limitations of this
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.