ArticleRadiology case reports2021
Cerebral syphilitic gumma presenting with intracranial gumma and pathologic vertebrae fractures.
Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- MRI of neurosyphilis with mesiotemporal lobe lesions of "knife-cut sign" on MRI: A case report and literature review.Heliyon · 2023Article
- Challenges in the Diagnosis of Tertiary Syphilis: Case Report with Literature Review.International journal of environmental research and public health · 2022Review
- Neurosyphilis in disguise.Neuroradiology · 2022Review
- Meningovascular Syphilis Presenting as a Brain Mass in an Immunocompetent Male.Open forum infectious diseases · 2021Article
- Syphilitic Gummata in the Central Nervous System: A Narrative Review and Case Report about a Noteworthy Clinical Manifestation.Microorganisms · 2021Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 37-year-old female was admitted with worsening neurologic function. On arrival from an outside hospital, the patient was obtunded and intubated. Magnetic resonance imaging of the brain revealed nodular enhancement of the leptomeninges, intracranial osteolytic lesions, and diffuse vasogenic edema causing mass effect. Imaging of the thoracic spine revealed pathologic compression fractures of 4 thoracic vertebrae. On review of the patient's electronic medical record, the patient had previously received treatment for secondary syphilis with intramuscular benzathine penicillin G. Surgical biopsies of the frontal bone and dura showed diffuse, chronic inflammation while a biopsy of the adjacent brain parenchyma revealed replicating spirochetes. The patient was subsequently prescribed dexamethasone and benzathine penicillin G. She regained neurologic function but later signed out against medical advice without completing her treatment regimen.
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Registered trials
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