ArticleAsian journal of pharmaceutical sciences2021
Alginate-based complex fibers with the Janus morphology for controlled release of co-delivered drugs.
Article in Asian journal of pharmaceutical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-Analysis of PKP or PVP Combined with Acupuncture in the Treatment of Osteoporotic Vertebral Compression Fractures.Contrast media & molecular imaging · 2022Pooled it
- Efficacy of Sequential Capecitabine on Adjuvant Chemotherapy of Triple-Negative Breast Cancer.Journal of healthcare engineering · 2022Trial
- Preparation of Sustainable Alginate/Chitosan Blend Films by Thermo-Compression for Diverse Applications.Gels (Basel, Switzerland) · 2026Article
- Synthesis, Characterization, and Study of the Bioactivity of Nanosized Fe(III) and Cr(III) Coordination Polymers Based on Cross-Linked Sodium Alginate and Polyacrylic Acid Biopolymers.International journal of biomaterials · 2026Article
- Bioinspired micro-structured fibers for biomedical applications.Bioactive materials · 2025Review
- "Double-sided protector" Janus hydrogels for skin and mucosal wound repair: applications, mechanisms, and prospects.Journal of nanobiotechnology · 2025Review
- Multifunctional Janus Hydrogels: Surface Design Strategies for Next-Generation Clinical Solutions.Gels (Basel, Switzerland) · 2025Review
- Insights into microscopic fabrication, macroscopic forms and biomedical applications of alginate composite gel containing metal-organic frameworks.Asian journal of pharmaceutical sciences · 2024Review
- A systematic review of astragaloside IV effects on animal models of diabetes mellitus and its complications.Heliyon · 2024Review
- Role of Polymer Concentration on the Release Rates of Proteins from Single- and Double-Network Hydrogels.International journal of molecular sciences · 2023Article
- Three-Dimensional Printing Multi-Drug Delivery Core/Shell Fiber Systems with Designed Release Capability.Pharmaceutics · 2023Article
- Transition Metal-Decorated MgACS omega · 2023Article
- The crosstalk between intestinal bacterial microbiota and immune cells in colorectal cancer progression.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Review
- Recent Approaches for Downplaying Antibiotic Resistance: Molecular Mechanisms.BioMed research international · 2023Review
- Article
- Roles and Mechanisms of Astragaloside IV in Combating Neuronal Aging.Aging and disease · 2022Review
- Integrated Bioinformatics-Based Subtractive Genomics Approach to Decipher the Therapeutic Drug Target and Its Possible Intervention against Brucellosis.Bioengineering (Basel, Switzerland) · 2022Article
- Study the nature of interaction between 5-Fluorouracil anti-cancer drug and borospherene.Journal of molecular modeling · 2022Article
- Controlled Delivery of an Anti-Inflammatory Toxin to Macrophages by Mutagenesis and Nanoparticle Modification.Nanomaterials (Basel, Switzerland) · 2022Article
- Magnesium oxide nanotube as a promising material for detection of methamphetamine drug: theoretical study.Journal of molecular modeling · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogels are soft materials consisting of a three-dimensional network of polymer chains. Over the years, hydrogels with different compositions have been developed as drug carriers for diverse biomedical applications, ranging from cancer therapy and wound care to the treatment of neurodegenerative and inflammatory diseases. Most of these carriers, however, are designed only to deliver single agents. Carriers based on hydrogels for co-delivery of multiple agents, with the release rate of each of the co-delivered agents tunable, are lacking. This study reports a one-pot method of fabricating alginate-based complex fibers with the Janus morphology, with carboxymethyl cellulose sodium functioning as a polymeric modifier of the properties of each of the fiber compartments. By using malachite green and minocycline hydrochloride as model drugs, the generated fibers demonstrate the capacity of enabling the release profile of each of the co-delivered drugs to be precisely controlled. Along with their negligible toxicity and the retention of the activity of the loaded drugs, the complex fibers reported in this study warrant further development and optimization for applications that involve co-delivery of multiple agents.
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Registered trials
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