Evidence map›Paper›PMID 33613700›Full record

ArticleTherapeutic advances in medical oncology2021

Real-life prognosis of 5041 bone-only metastatic breast cancer patients in the multicenter national observational ESME program.

Marion Bertho, Julien Fraisse, Anne Patsouris, Paul Cottu, Monica Arnedos, David Pérol, Anne Jaffré, Anthony Goncalves, Marie-Paule Lebitasy, Véronique D'Hondt and 14 more

Registry-linked trialAbstract read
In one paragraph

Article in Therapeutic advances in medical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03275311 (Epidemiological Strategy and Medical Economic), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03275311 recruitingnot on this map

Epidemiological Strategy and Medical Economic (ESME) Research Program / Academic Real World Database: Evolution of the Therapeutic Care in Metastatic Breast Cancer Across the French Comprehensive Cancer Centers From 2008

TypeobservationalSponsorUNICANCERRan2014 to 2027Enrolled42,000ConditionsMetastatic Breast Cancer
3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Marion BerthoDepartment of Medical Oncology, Institut de Cancérologie de l'Ouest - Paul Papin, Angers, France.ORCID https://orcid.org/0000-0001-6992-9174
Julien FraisseBiometrics Unit, Regional Cancer Institute of Montpellier (ICM), Montpellier, France.
Anne PatsourisDepartment of Medical Oncology, Institut de Cancérologie de l'Ouest - Paul Papin, Angers, France.
Paul CottuDepartment of Medical Oncology, Institut Curie, Paris, France.
Monica ArnedosDepartment of Medical Oncology, Gustave Roussy Cancer Campus, Villejuif, France.
David PérolBiostatistic Unit, Clinical Research and Innovation Department, Centre Léon Bérard, Lyon, France.
Anne JaffréDepartment of Medical Information, Institut Bergonié, Bordeaux, France.
Anthony GoncalvesDepartment of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Marie-Paule LebitasyClinical Research and Innovation Department, Centre Oscar Lambret, Lille, France.
Véronique D'HondtDepartment of Medical Oncology, Institut du Cancer de Montpellier, Montpellier, France.
Florence DalencDepartment of Medical Oncology, Institut Claudius Regaud, IUCT-Oncopole, Toulouse, France.
Jean-Marc FerreroDepartment of Medical Oncology, Institut Centre Antoine Lacassagne, Nice, France.
Christelle LevyDepartment of Medical Oncology, Centre François Baclesse, Caen, France.
Sandrine DabakuyoNational Quality of Life and Cancer Clinical Research Platform, Centre Georges François Leclerc, Dijon, France.
Roman RouzierDepartment of Surgical Oncology, Institut Curie, Saint-Cloud, France.
Frédérique Penault-LlorcaDepartment of Pathology and Molecular Pathology, Centre Jean Perrin, Clermont Ferrand, France.
Lionel UwerDepartment of Medical Oncology, Institut de Cancérologie de Lorraine, Vandoeuvre-lès- Nancy, France.
Jean-Christophe EymardDepartment of Medical Oncology, Institut de Cancérologie Jean-Godinot, Reims, France.
Mathias BretonDepartment of Medical Information, Centre Eugène Marquis, Rennes, France.
Michaël ChevrotUNICANCER R&D, Paris, France.
Sébastien ThureauDepartment of Radiation Oncology, Centre Henri Becquerel, Rouen, France.
Thierry PetitDepartment of Medical Oncology, Centre Paul Strauss, Strasbourg, France.
Gaëtane SimonUNICANCER R&D, Paris, France.
Jean-Sébastien FrénelDepartment of Medical Oncology, ICO René Gauducheau, Boulevard Jacques Monod, Saint Herblain, Pays de la Loire 44805, France.ORCID https://orcid.org/0000-0002-5273-0561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBone-only (BO) metastatic breast cancer (MBC) is considered a more favorable entity than other MBC presentations. However, only few retrospective series and data from selected randomized controlled trials have been reported so far.

methodsUsing the French national multicenter ESME (Epidemiological Strategy and Medico Economics) Data Platform, the primary objective of our study was to compare the overall survival (OS) of patients with BO

resultsOut of 20,095 eligible women, 5041 (22.4%) patients had BO disease [hormone-receptor positive (HR+)/human epidermal growth-factor-receptor-2 negative (HER2-),

conclusionBO MBC patients have better outcomes compared with non-BO MBC, consistently, through all MBC subtypes.

Indexed as

bone-onlymetastatic breast canceroutcomesoverall survivalreal-lifetreatments

Identifiers

PMID33613700
PMCPMC7841864

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.