ArticleInternational journal of endocrinology and metabolism2020
Article in International journal of endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- The evaluation of risk factors in fascia dehiscence after abdominal surgeries.Annals of medicine and surgery (2012) · 2024Article
- Identification of Tumor Budding-Associated Genes in Breast Cancer through Transcriptomic Profiling and Network Diffusion Analysis.Biomolecules · 2024Article
- NOL4 is a novel nuclear marker of small cell carcinoma and other neuroendocrine neoplasms.Histology and histopathology · 2022Article
- Hemodynamic stability during menstrual cycle in women undergoing elective surgery.Annals of medicine and surgery (2012) · 2022Article
- Comparison of the prevalence of perforated appendicitis during and before COVID19 pandemic.Annals of medicine and surgery (2012) · 2022Article
- Evaluation of serum levels of cathepsin S among colorectal cancer patients.Annals of medicine and surgery (2012) · 2022Article
- Methylation of FBN1, SPG20, ITF2, RUNX3, SNCA, MLH1, and SEPT9 genes in circulating cell-free DNA as biomarkers of colorectal cancer.Cancer biomarkers : section A of Disease markers · 2022Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroid cancer is the fourth most common cancer in the world. Papillary thyroid carcinoma (PTC) accounts for 80% of all types of thyroid neoplasm. Epigenetic alterations such as DNA methylation are known as the main cause of different types of cancers through inactivation of tumor suppressor genes.
objectivesIn the present study, the expression and methylation of suggested gene namely nucleolar protein 4 (
methodsForty-one patients with PTC and 38 patients affected by MNG were recruited. Thyroid tissues were obtained during thyroidectomy. RNA and DNA were extracted from thyroid tissues. Quantitative RT-PCR assay was performed for determining the mRNA level of
resultsMethylation assessment of 81 CpG islands in the promoter region of
conclusionsThese data suggested an aberrant promoter hyper-methylation of
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Registered trials
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