Evidence map›Paper›PMID 33613528›Full record

SynthesisFrontiers in immunology2020

Outcome Predictors of Biopsy-Proven Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody-Associated Glomerulonephritis.

Yifei Ge, Guang Yang, Xiangbao Yu, Bin Sun, Bo Zhang, Yanggang Yuan, Ming Zeng, Ningning Wang, Huijuan Mao, Changying Xing

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yifei GeDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Guang YangDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiangbao YuDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Bin SunDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Bo ZhangDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yanggang YuanDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ming ZengDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ningning WangDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Huijuan MaoDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Changying XingDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine the prognostic values of histopathologic classification of myeloperoxidase-anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis and other clinical and laboratory features at the time of presentation on renal and patient survival associated with myeloperoxidase-ANCA-associated glomerulonephritis (MPO-ANCA-GN). Methods: A total of 112 patients diagnosed with MPO-ANCA-GN from October 2005 to December 2018 were enrolled. The baseline clinical characteristics, renal histopathological data, and risk factors predictive of renal and patient survival were retrospectively analyzed. Results: All 112 patients underwent renal biopsy. Disease in 32 patients was classified as focal, 26 as mixed, 29 as crescentic, and 25 as sclerotic. Over a median follow-up period of 41.5 months, there were 44 patients dialysis-dependent. The renal survival rate was significantly higher in the focal group than the other groups ( Conclusion: Among patients with MPO-ANCA-GN, those with poor renal function, disease histopathologically classified as sclerotic, and lower albumin and hemoglobin levels were risk factors for ESRD, while older age and low serum albumin level were associated with a greater risk for all-cause mortality.

Indexed as

AgedAge FactorsAntibodies, Antineutrophil CytoplasmicAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisBiopsyDisease ProgressionFemaleGlomerulonephritisGlucocorticoidsHemoglobinsHumansKidney GlomerulusMaleMiddle AgedPeroxidasePredictive Value of TestsALB protein, humanAntibodies, Antineutrophil CytoplasmicGlucocorticoidsHemoglobinsMPO protein, humanPeroxidaseSerum Albumin, Humanhistopathologic classificationmyeloperoxidase-anti-neutrophil cytoplasmic antibody-associated glomerulonephritispatient survivalrenal survivalvasculitis

Identifiers

PMID33613528
PMCPMC7889806
OpenAlexW3128844562

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.