Evidence map›Paper›PMID 33613471›Full record

ArticleFrontiers in microbiology2020

Metagenomics Reveals That Intravenous Injection of Beta-Hydroxybutyric Acid (BHBA) Disturbs the Nasopharynx Microflora and Increases the Risk of Respiratory Diseases.

Jiancheng Qi, Dongjie Cai, Yaocheng Cui, Tianyu Tan, Huawei Zou, Wei Guo, Yue Xie, Hongrui Guo, Shi-Yi Chen, Xiaoping Ma and 16 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 3 institutions in 2 countries.

Jiancheng QiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Dongjie CaiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yaocheng CuiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Tianyu TanCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Huawei ZouInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Wei GuoDepartment of Clinical Laboratory, Chengdu Medical College, Chengdu, China.
Yue XieCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Hongrui GuoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shi-Yi ChenCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
Xiaoping MaCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Liping GouCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Hengmin CuiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yi GengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ming ZhangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
Gang YeCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Zhijun ZhongCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Zhihua RenCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yanchun HuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ya WangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Junliang DengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shumin YuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Suizhong CaoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Metha WanapatTropical Feed Resources Research and Development Center (TROFREC), Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen, Thailand.
Jing FangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Zhisheng WangInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Zhicai ZuoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sichuan Agricultural University · CNChengdu Medical College · CNKhon Kaen University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is widely accepted that maintenance of microbial diversity is essential for the health of the respiratory tract; however, there are limited reports on the correlation between starvation and respiratory tract microbial diversity. In the present study, saline/β-hydroxybutyric acid (BHBA) intravenous injection after dietary restriction was used to imitate different degrees of starvation. A total of 13 healthy male yaks were imposed to different dietary restrictions and intravenous injections, and their nasopharyngeal microbiota profiles were obtained by metagenomic shotgun sequencing. In healthy yaks, the main dominant phyla were

Indexed as

metagenomicsmicrobial diversitynasopharynx microbiotarespiratory tractstarvationyak

Identifiers

PMID33613471
PMCPMC7892611
OpenAlexW3128072098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.