Evidence map›Paper›PMID 33613435›Full record

ArticleFrontiers in neurology2021

The Role of Frontal Assessment Battery and Frontal Lobe Single-Photon Emission Computed Tomography in the Differential Diagnosis of Progressive Supranuclear Palsy Variants and Corticobasal Syndrome-A Pilot Study.

Piotr Alster, Bartosz Migda, Natalia Madetko, Karolina Duszyńska-Wąs, Agnieszka Drzewińska, Ingeborga Charzyńska, Miłosz Starczyński, Ada Szepelska, Leszek Królicki, Andrzej Friedman

Abstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Piotr AlsterDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Bartosz MigdaUltrasound Diagnostic Department, Faculty of Medical Sciences, Medical University of Warsaw, Warsaw, Poland.
Natalia MadetkoDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Karolina Duszyńska-WąsDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Agnieszka DrzewińskaDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Ingeborga CharzyńskaDepartment of Nuclear Medicine and Magnetic Resonance, Mazowiecki Hospital Brodnowski, Warsaw, Poland.
Miłosz StarczyńskiDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Ada SzepelskaDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Leszek KrólickiDepartment of Nuclear Medicine, University Clinical Center, Medical University of Warsaw, Warsaw, Poland.
Andrzej FriedmanDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are clinical syndromes classified as atypical parkinsonism. Due to their overlapping symptomatology, recent research shows the necessity of finding new methods of examination of these clinical entities. PSP is a heterogenic disease. PSP Richardson-Steele Syndrome (PSP-RS) and parkinsonism predominant (PSP-P) are the most common clinical variants of progressive supranuclear palsy syndrome. The different clinical course and life expectancy of PSP-RS and PSP-P stress the need of efficient examination in the early stages. The aim of the study was to evaluate the possible feasibility of the combined use of frontal assessment battery (FAB) and single-photon emission computed tomography (SPECT) in the differentiation of PSP-RS, PSP-P, and CBS. The findings show that FAB may be interpreted as a possible supplementary tool in the differential diagnosis of PSP-P and PSP-RS. The differences in SPECT are less pronounced. The study does not show any advantages of performing combined frontal SPECT and FAB in the differential examination of PSP and CBS. Moreover, PSP-RS and CBS, in a detailed evaluation of the frontal lobe, do not show any significant differences. This is a relatively small study which, however, highlights the relevant features of clinical examination of these rare entities.

Indexed as

frontal lobeparkinsonismprogressive supranuclear palsySPECTtauopathies

Identifiers

PMID33613435
PMCPMC7891101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.