Evidence map›Paper›PMID 33613231›Full record

ArticleCase reports in dermatology

Multifocal Langerhans Cell Histiocytosis: A Unique Presentation of Eosinophilic Granuloma with Intracranial Extension, Massive Lymphadenopathy, and Epstein-Barr Viral Infection in an Adolescent Female.

Kent Wade Foster, Shamika Kayo Robinson, Eleanor Tung-Hahn, George Gibbons, Carl Wayne Cruse, Kumaran Mudaliar, Rebecca Tung, Wendy Kim

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kent Wade FosterDepartment of Biology, Brigham Young University, Provo, Utah, USA.
Shamika Kayo RobinsonDivision of Dermatology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.
Eleanor Tung-HahnDepartment of Public Health, The University of South Florida, Tampa, Florida, USA.
George GibbonsDermpath Diagnostics, Tampa, Florida, USA.
Carl Wayne CruseCutaneous Oncology Program, Moffitt Cancer Center, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Kumaran MudaliarDepartment of Pathology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.
Rebecca TungFlorida Dermatology and Skin Cancer Centers, Winter Haven, Florida, USA.
Wendy KimDivision of Dermatology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.
Loyola University Chicago · USBrigham Young University · USMoffitt Cancer Center · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of an otherwise healthy 17-year-old female who presented for surgical removal of an enlarging "atypical cyst" on her scalp. During subtotal excision, only friable serosanguinous translucent ribbons of tissue were found. A histopathologic diagnosis of Langerhans cell histiocytosis (LCH) was rendered and imaging studies revealed extradural invasion of the tumor. Within weeks, the patient also developed progressive lymphadenopathy with grossly elevated levels of Epstein-Barr virus viral capsid antigen antibody levels. This report aims to highlight a unique presentation of LCH with discussion of workup, management, and avoidance of potential surgical complications.

Indexed as

Eosinophilic granulomaEpstein-Barr virusIntracranial extensionLymphadenopathyMultifocal Langerhans cell histiocytosis

Identifiers

PMID33613231
PMCPMC7879306
OpenAlexW3121227971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.