Evidence map›Paper›PMID 33613192›Full record

ReviewFrontiers in molecular neuroscience2021

Rapid and Reversible Development of Axonal Varicosities: A New Form of Neural Plasticity.

Chen Gu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Chen GuDepartment of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, United States.
The Ohio State University · US

Funding

Polarized Initiation of Varicosity Formation in Central Neuron MechanosensationR01NS093073 · NINDS · OHIO STATE UNIVERSITY · PI GU, CHEN · 2016 to 2025
$3.3M
NINDS NIH HHS R01 NS093073
6 · The paper itself

Abstract

Axonal varicosities are enlarged, heterogeneous structures along axonal shafts, profoundly affecting axonal conduction and synaptic transmission. They represent a key pathological feature believed to develop via slow accumulation of axonal damage that occurs during irreversible degeneration, for example in mild traumatic brain injury (mTBI), Alzheimer's and Parkinson's diseases, and multiple sclerosis. Here this review first discusses recent

Indexed as

action potentialAlzheimer's diseaseaxonal varicositymechanosensitive ion channelmicrotubulemild traumatic brain injuryneural plasticitysynaptic transmission

Identifiers

PMID33613192
PMCPMC7886671
OpenAlexW3127127771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.