Evidence map›Paper›PMID 33612858›Full record

ArticleJournal of molecular structure2021

"Identification of Nafamostat and VR23 as COVID-19 drug candidates by targeting 3CL

Deep Bhowmik, Ravi Datta Sharma, Amresh Prakash, Diwakar Kumar

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular structure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  8. RSC advances · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Deep BhowmikDepartment of Microbiology, Assam University, Silchar-788011, Assam, India.
Ravi Datta SharmaAmity Institute of Biotechnology, Amity University Haryana, Gurgaon-122413, India.
Amresh PrakashAmity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon-122413, India.
Diwakar KumarDepartment of Microbiology, Assam University, Silchar-788011, Assam, India.
Assam University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sudden increase in the COVID-19 epidemic affected by novel coronavirus 2019 has jeopardized public health worldwide. Hence the necessities of a drug or therapeutic agent that heal SARS-CoV-2 infections are essential requirements. The viral genome encodes a large Polyprotein, further processed by the main protease/ 3C-like protease (3CL

Indexed as

3CLproADMETand SimulationDockingDrugPLproSARS-CoV-2

Identifiers

PMID33612858
PMCPMC7884051
OpenAlexW3132479892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.