Evidence map›Paper›PMID 33612558›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2021

Optimization of Analytical Procedure for In-hospital Rapid Quantification of Serum Level of Favipiravir in the Pharmacological Treatment of COVID-19.

Yukiko Moriiwa, Go Morikawa, Katsuko Okazawa, Akio Yanagida

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yukiko Moriiwa *Department of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan. moriiwa@toyaku.ac.jp.
Go Morikawa *Department of Pharmacy, Hokushin General Hospital, 1-5-63 Nishi, Nakano, Nagano, 383-8505, Japan. gomorikawa@hokushinhosp.jp.
Katsuko OkazawaDepartment of Pharmacy, Hokushin General Hospital, 1-5-63 Nishi, Nakano, Nagano, 383-8505, Japan.
Akio YanagidaDepartment of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An in-hospital rapid method for quantifying the serum level of favipiravir (FPV) in the pharmacological treatment of COVID-19 was developed by an appropriate combination of a solid-phase extraction treatment and a reversed-phase HPLC/UV detection system. The quantification method was well-validated and applied to measuring the serum FPV level in a clinical practice at a general hospital that accepts COVID-19 patients. Furthermore, an analysis of data from our preliminary interaction analysis revealed, for the first time, that FPV selectively forms complexes with ferric (Fe

Indexed as

AmidesAntiviral AgentsCOVID-19 Drug TreatmentPyrazinesChromatography, High Pressure LiquidCOVID-19HumansPhosphoramidesSARS-CoV-2Solid Phase ExtractionAmidesAntiviral AgentsfavipiravirPhosphoramidesPyrazinesCOVID-19favipiravirferric ionHPLCIn-hospital quantificationserum levelsolid-phase extraction

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.