Evidence map›Paper›PMID 33612134›Full record

ArticleEpidemiology and infection2021

Hantavirus-

K Jeske, J Jacob, S Drewes, M Pfeffer, G Heckel, R G Ulrich, C Imholt

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Detection of two zoonotic pathogens,One health (Amsterdam, Netherlands) · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. White-Toothed Shrews (GenusPathogens (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Genetic diversity ofFrontiers in cellular and infection microbiology · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Exposure of Free-Ranging Wild Animals to ZoonoticAnimals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

K JeskeInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493Greifswald-Insel Riems, Germany.ORCID 0000-0001-8573-4588
J JacobVertebrate Research, Institute for Plant Protection in Horticulture and Forests, Julius Kühn-Institute, Toppheideweg 88, 48161Münster, Germany.ORCID 0000-0002-5136-6606
S DrewesInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493Greifswald-Insel Riems, Germany.ORCID 0000-0003-1240-147X
M PfefferInstitute of Animal Hygiene and Veterinary Public Health, University of Leipzig, An den Tierkliniken 1, 04103Leipzig, Germany.ORCID 0000-0002-2457-8224
G HeckelInstitute of Ecology and Evolution, University of Bern, Baltzerstrasse 6, 3012Bern, Switzerland.ORCID 0000-0002-0162-323X
R G UlrichInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493Greifswald-Insel Riems, Germany.ORCID 0000-0002-5620-1528
C ImholtVertebrate Research, Institute for Plant Protection in Horticulture and Forests, Julius Kühn-Institute, Toppheideweg 88, 48161Münster, Germany.ORCID 0000-0002-7504-9509
Friedrich-Loeffler-Institut · DEJulius Kühn-Institut · DELeipzig University · DEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

European orthohantaviruses (Puumala orthohantavirus (PUUV); Dobrava-Belgrade orthohantavirus (DOBV), genotype Kurkino; Tula orthohantavirus (TULV)), and Leptospira spp. are small mammal-associated zoonotic pathogens that cause diseases with potentially similar symptoms in humans. We investigated the frequency of Leptospira spp. and hantavirus single and double infections in small mammals from 22 sites in Thuringia, central Germany, during 2017. TULV infections were detected at 18 of 22 sites (mean prevalence 13.8%, 93/674). PUUV infections were detected at four of 22 sites (mean prevalence 1.5%, 7/471), and respective PUUV sequences formed a novel phylogenetic clade, but DOBV infections were not detected at all. Leptospira infections were detected at 21 of 22 sites with the highest overall prevalence in field voles (Microtus agrestis) with 54.5% (6/11) and common voles (Microtus arvalis) with 30.3% (205/676). Leptospira-hantavirus coinfections were found in 6.6% (44/671) of common voles but only in two of 395 bank voles. TULV and Leptospira coinfection probability in common voles was driven by individual (age) and population-level factors. Coinfections seemed to be particularly associated with sites where Leptospira spp. prevalence exceeded 35%. Future investigations should evaluate public health consequences of this strong spatial clustering of coinfections.

Indexed as

AnimalsArvicolinaeCoinfectionDNA, BacterialGermanyHantavirus InfectionsLeptospiraLeptospirosisOrthohantavirusPhylogenyRNA, ViralRodent DiseasesDNA, BacterialRNA, ViralCoinfectioncommon voleLeptospira spp.Puumala orthohantavirusTula orthohantavirus

Identifiers

PMID33612134
PMCPMC8101269
OpenAlexW3132958674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.