Evidence map›Paper›PMID 33611935›Full record

ReviewHypertension (Dallas, Tex. : 1979)2021

Effect of Sleep Disturbances on Blood Pressure.

Nour Makarem, Carmela Alcántara, Natasha Williams, Natalie A Bello, Marwah Abdalla

Open access · bronzeAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Sleep, Neural Circulatory Control, and Cardiovascular Disease: A Mechanistic Review.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
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  18. Hypertension due to financial mismanagement.Frontiers in public health · 2026
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nour MakaremFrom the Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY (N.M.).
Carmela AlcántaraSchool of Social Work, Columbia University, NY (C.A.).
Natasha WilliamsDepartment of Population Health, Center for Healthful Behavior Change, New York University Grossman School of Medicine (N.W.).
Natalie A BelloDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, NY (N.A.B., M.A.).
Marwah AbdallaDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, NY (N.A.B., M.A.).
Columbia University Irving Medical Center · USColumbia University · USNew York University · US

Funding

Automated clinic blood pressure assessment and detection of white coat and masked hypertension study in African AmericansR01HL146636 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABDALLA, MARWAH · 2020 to 2025
$3.8M
Using eHealth to Expand Access to Cognitive Behavioral Therapy for Insomnia in Hispanic Primary Care PatientsR01HS024274 · AHRQ · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ALCANTARA, CARMELA · 2018 to 2022
$1.9M
Cardiac Manifestations of PreeclampsiaR01HL153382 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2020 to 2023
$1.6M
Adherence to PAP Treatment: Influences of Co-Morbid Insomnia and of Race/EthnicityK23HL125939 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WILLIAMS, NATASHA J · 2015 to 2019
$1.2M
Nocturnal Hypertension and SleepK23HL141682 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABDALLA, MARWAH · 2019 to 2023
$953k
Blood Pressure Measurement and Hypertension in PregnancyK23HL136853 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2018 to 2022
$948k
Identifying Novel Behavioral Targets for Improving Sleep: A Self-Regulation ModelK23HL125748 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ALCANTARA, CARMELA · 2015 to 2019
$924k
CIRCADIAN PATTERN OF REST-ACTIVITY RHYTHMS AND BLOOD PRESSURE AND THE UNDERLYINGR00HL148511 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAKAREM, NOUR · 2021 to 2023
$809k
Circadian Pattern of Rest-Activity Rhythms and Blood Pressure and the Underlying Epigenetic MechanismsK99HL148511 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAKAREM, NOUR · 2019 to 2020
$259k
AHRQ HHS R01 HS024274American Heart Association-American Stroke Association 18AMFDP34380732NHLBI NIH HHS K23 HL125748NHLBI NIH HHS K23 HL125939NHLBI NIH HHS K23 HL136853NHLBI NIH HHS K23 HL141682NHLBI NIH HHS K99 HL148511NHLBI NIH HHS R00 HL148511NHLBI NIH HHS R01 HL146636NHLBI NIH HHS R01 HL153382
6 · The paper itself

Abstract

This review summarizes recent literature addressing the association of short sleep duration, shift work, and obstructive sleep apnea with hypertension risk, blood pressure (BP) levels, and 24-hour ambulatory BP. Observational studies demonstrate that subjectively assessed short sleep increases hypertension risk, though conflicting results are observed in studies of objectively assessed short sleep. Intervention studies demonstrate that mild and severe sleep restriction are associated with higher BP. Rotating and night shift work are associated with hypertension as shift work may exacerbate the detrimental impact of short sleep on BP. Further, studies demonstrate that shift work may increase nighttime BP and reduce BP control in patients with hypertension. Finally, moderate to severe obstructive sleep apnea is associated with hypertension, particularly resistant hypertension. Obstructive sleep apnea is also associated with abnormal 24-hour ambulatory BP profiles, including higher daytime and nighttime BP, nondipping BP, and a higher morning surge. Continuous positive airway pressure treatment may lower BP and improve BP dipping. In conclusion, efforts should be made to educate patients and health care providers about the importance of identifying and treating sleep disturbances for hypertension prevention and management. Empirically supported sleep health interventions represent a critical next step to advance this research area and establish causality.

Indexed as

HypertensionHealth BehaviorHeart Disease Risk FactorsHumansSleep Apnea, ObstructiveSleep HygieneSleep Wake Disordersblood pressurehealth behaviorhypertensionpolysomnographysleep

Identifiers

PMID33611935
PMCPMC7946733
OpenAlexW3132060350

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.