Evidence map›Paper›PMID 33611718›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021

Comparison of anterior-only versus combined anterior and posterior fusion for unstable subaxial cervical injuries: a meta-analysis of biomechanical and clinical studies.

Dong-Yeong Lee, Young-Jin Park, Myung-Geun Song, Kun-Tae Kim, Dong-Hee Kim

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The correlation between biomechanical experiments and clinical studies in orthopedics: a systematic review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Pooled it
  2. Article
  3. Clinical and radiological outcomes of one-level cervical corpectomy with an expandable cage for three-column uncomplicated subaxial type «B» injures: a multicenter retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong-Yeong LeeDepartment of Orthopaedic Surgery, Barun Hospital, Jinju, Republic of Korea.
Young-Jin ParkDepartment of Orthopaedic Surgery and Institute of Health Science, Gyeongsang National University Hospital and Gyeongsang National University College of Medicine, 15, Jinju-daero 816 beon-gil, Jinju-si, 660-751, Gyeongsangnam-do, Republic of Korea.
Myung-Geun SongDepartment of Orthopaedic Surgery and Institute of Health Science, Gyeongsang National University Hospital and Gyeongsang National University College of Medicine, 15, Jinju-daero 816 beon-gil, Jinju-si, 660-751, Gyeongsangnam-do, Republic of Korea.
Kun-Tae KimDepartment of Orthopaedic Surgery and Institute of Health Science, Gyeongsang National University Hospital and Gyeongsang National University College of Medicine, 15, Jinju-daero 816 beon-gil, Jinju-si, 660-751, Gyeongsangnam-do, Republic of Korea.
Dong-Hee KimDepartment of Orthopaedic Surgery and Institute of Health Science, Gyeongsang National University Hospital and Gyeongsang National University College of Medicine, 15, Jinju-daero 816 beon-gil, Jinju-si, 660-751, Gyeongsangnam-do, Republic of Korea. dhkim8311@gnu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of the present study was to perform a meta-analysis comparing biomechanical and clinical outcomes between anterior-only and combined anterior and posterior fusions to determine which method of cervical fusion yielded better results for unstable cervical injuries.

methodsThe MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science and SCOPUS electronic databases were searched for relevant articles published through 2000-2019 that compared the biomechanical and clinical outcomes of anterior-only and combined anterior and posterior fusion for unstable cervical fracture.

resultsEight biomechanical and four clinical studies were included in the analysis. There were significant biomechanical differences between the groups with respect to flexion-extension, axial rotation and lateral bending. Combined fusion provided better biomechanical stability for unstable cervical injuries than anterior-only fusion, regardless of the number of corpectomies or the presence of a posterior column injury. However, despite significant biomechanical differences, there were no significant differences in clinical outcomes, such as the degree of neurologic improvement and complications between the two groups.

conclusionAnterior-only and combined anterior and posterior fusions for unstable subaxial cervical injuries can both restore cervical stability. Although combined fusion might have some advantages in terms of stability biomechanically, there were no significant differences in clinical outcomes, such as the degree of neurologic improvement and perioperative complications. Therefore, rather than the routine use of combined fusion for unstable cervical injuries, the selective use of anterior-only or combined fusion according to the type of injury is recommended.

Indexed as

Joint InstabilitySpinal FusionBiomechanical PhenomenaCervical VertebraeHumansRange of Motion, ArticularRotationAnterior-only procedureCervical spineCombined procedureSpinal fusionUnstable fracture

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.