ReviewJournal of neuro-oncology2021
Surgical strategy for insular glioma.
Review in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Transcortical versus transsylvian approaches for adult insular glioma resection: a systematic review with subanalysis by Berger-Sanai segmentation.Neurosurgical review · 2026Pooled it
- A Journey into the Complexity of Temporo-Insular Gliomas: Case Report and Literature Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Transcortical versus Transsylvian Approach for Insular Gliomas: A Systematic Review and Meta-Analysis.Asian journal of neurosurgery · 2026Review
- Corynoline promotes apoptosis and inhibits proliferation of glioblastoma via regulating the STAT3/Bcl-2 signalling pathway.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- The specific linear or curved boundaries between WHO grade II-III insular gliomas and the basal ganglia indicate distinct biological features, survival outcomes, and surgical strategies: evidence from 330 cases.NeuroImage. Clinical · 2026Article
- Surgical timing guided by progressive cognitive decline in a left insular tumor without neurological deficits: A case report.Surgical neurology international · 2026Article
- Anatomical references for the transopercular approach to the insula: a 1.5 Tesla magnetic resonance study.Neurosurgical review · 2025Article
- Second harmonic generation for brain imaging: pathology-related studies.Biophysical reviews · 2025Article
- Case Study of an Unusual Intracranial Mesenchymal Neoplasm.Neurosurgery practice · 2025Article
- Potential predictors of awake surgery failure for insular glioma.Scientific reports · 2025Article
- Overcoming Barriers in Neurosurgical Education: Introducing a Simulator for Insular Glioma Resection with Fluorescence Imaging (SIGMA).Journal of clinical medicine · 2025Article
- Safety and Efficacy in the Transcortical and Transsylvian Approach in Insular High-Grade Gliomas: A Comparative Series of 58 Patients.Current oncology (Toronto, Ont.) · 2025Article
- Utilizing multiple diffusion metrics in evaluation of corticospinal tract injury in patients with glioblastoma.Frontiers in neuroscience · 2025Article
- Association between serum response factor, microvascular density, and postoperative recurrence in glioma patients.American journal of translational research · 2025Article
- Mini-strokes within Broca-caudate connections during left insular glioma awake surgery cause transient severe naming deficits.Acta neurochirurgica · 2024Article
- Potential Mechanism and Involvement of p120-Catenin in the Malignant Biology of Glioma.Journal of Korean Neurosurgical Society · 2024Article
- Extra-temporal pediatric low-grade gliomas and epilepsy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- CHI3L1 as a Prognostic Biomarker and Therapeutic Target in Glioma.International journal of molecular sciences · 2024Article
- Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression.Biology direct · 2024Article
- Identification and validation of prognostic genes and immune landscape signatures based on a fatty acid oxidation‑related risk score model in glioma.Oncology letters · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe goal of this article is to review the outcomes of insular glioma surgery and discuss strategies to minimize postoperative morbidity.
methodsThe authors reviewed the published literature on low- and high-grade insular gliomas with a focus on glioma biology, insular anatomy, and surgical technique.
resultsMaximal safe resection of insular gliomas is associated with improved survival and is the primary goal of surgery. Protecting patient speech and motor function during insular glioma resection requires versatile integration of insular anatomy, cortical mapping, and microsurgical technique. Both the transsylvian and transcortical corridors to the insula are associated with low morbidity profiles, but the transcortical approach with intraoperative mapping is more favorable for gliomas within the posterior insular region.
conclusionsSurgical strategy for insular gliomas is dependent on biological, anatomical, and clinical factors. Technical mastery integrated with intraoperative technologies can optimize surgical results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.