ReviewJournal of neuro-oncology2021
Laser interstitial thermotherapy (LITT) for the treatment of tumors of the brain and spine: a brief review.
Review in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
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Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Imaging-based techniques for ablation zone definition and volumetry after laser interstitial thermal therapy (LITT) for intracranial lesions: a systematic review.Acta neurochirurgica · 2025Pooled it
- Comparative analysis of bevacizumab and LITT for treating radiation necrosis in previously radiated CNS neoplasms: a systematic review and meta-analysis.Journal of neuro-oncology · 2024Pooled it
- Meta-analysis of the impact of laser interstitial hyperthermia on wound healing complications in brain tumors.International wound journal · 2024Pooled it
- Outcomes of Laser Interstitial Thermal Therapy-Augmented Surgery in the Management of Subcortical Glioblastoma.Neurosurgery practice · 2026Article
- Surgery of the tumors of the spine.EFORT open reviews · 2026Article
- Review
- Laser Interstitial Thermal Therapy for High-Grade Gliomas: Current Evidence, Clinical Applications and Emerging Role of Artificial Intelligence.Journal of clinical medicine · 2026Review
- Laser interstitial thermal therapy for the ablation of pediatric low-grade glioma: a single-institution series of 13 patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Model Predictive Filtering MR Temperature Imaging for Laser-Induced Interstitial Thermotherapy.Magnetic resonance in medicine · 2026Article
- Modified tubular retractor for deep brain tumour resection: enhanced surgical outcomes in resource-constrained settings.Neurosurgical review · 2026Article
- Noninvasive detection and prediction method for temperature inJournal of biomedical optics · 2026Article
- Temperature-induced hemoglobin dynamics: oxygenation-dependent evolution of hemoglobin spectral response in the near-infrared.Biophotonics discovery · 2026Article
- Laser interstitial thermal therapy for hemorrhagic subcortical cavernous malformations: patient series.Journal of neurosurgery. Case lessons · 2026Article
- How I do it: sequential robot-assisted stereotactic biopsy and laser interstitial thermal therapy for epilepsy associated with brain tumors.Acta neurochirurgica · 2025Article
- Sodium alginate-based tissue-mimicking phantom with tunable optical properties for laser thermotherapy.Biomedical optics express · 2025Article
- Volumetric and diffusion MRI longitudinal patterns in brain metastases after laser interstitial thermal therapy.European radiology · 2025Article
- Localized treatment of glioblastoma: a review of clinical strategies and advances in drug delivery systems.Nanomedicine (London, England) · 2025Review
- Predictors of prolonged length of stay in patients undergoing laser interstitial thermal therapy for intracranial tumors.Journal of neuro-oncology · 2025Article
- Ablative Techniques for the Management of Osseous Spine Metastases: A Narrative Review.Journal of clinical medicine · 2025Review
- Emerging Technologies in Radiation Therapy: Replacing Traditional Isotope-based Modalities.Health physics · 2025Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLaser Interstitial Thermotherapy (LITT; also known as Stereotactic Laser Ablation or SLA), is a minimally invasive treatment modality that has recently gained prominence in the treatment of malignant primary and metastatic brain tumors and radiation necrosis and studies for treatment of spinal metastasis has recently been reported.
methodsHere we provide a brief literature review of the various contemporary uses for LITT and their reported outcomes.
resultsHistorically, the primary indication for LITT has been for the treatment of recurrent glioblastoma (GBM). However, indications have continued to expand and now include gliomas of different grades, brain metastasis (BM), radiation necrosis (RN), other types of brain tumors as well as spine metastasis. LITT is emerging as a safe, reliable, minimally invasive clinical approach, particularly for deep seated, focal malignant brain tumors and radiation necrosis. The role of LITT for treatment of other types of tumors of the brain and for spine tumors appears to be evolving at a small number of centers. While the technology appears to be safe and increasingly utilized, there have been few prospective clinical trials and most published studies combine different pathologies in the same report.
conclusionWell-designed prospective trials will be required to firmly establish the role of LITT in the treatment of lesions of the brain and spine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.