Evidence map›Paper›PMID 33611614›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Weakly supervised deep learning for determining the prognostic value of

Rui Guo, Xiaobin Hu, Haoming Song, Pengpeng Xu, Haoping Xu, Axel Rominger, Xiaozhu Lin, Bjoern Menze, Biao Li, Kuangyu Shi

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  15. American journal of nuclear medicine and molecular imaging · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Rui Guo *Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaobin Hu *Department of Informatics, Technical University of Munich, Munich, Germany.
Haoming Song *Department of Informatics, Technical University of Munich, Munich, Germany.
Pengpeng XuState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haoping XuDepartment of Radiation, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Axel RomingerDepartment of Nuclear Medicine, University of Bern, Bern, Switzerland.
Xiaozhu LinDepartment of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bjoern MenzeDepartment of Informatics, Technical University of Munich, Munich, Germany.
Biao LiDepartment of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lb10363@rjh.com.cn.ORCID 0000-0002-0493-2062
Kuangyu ShiDepartment of Informatics, Technical University of Munich, Munich, Germany.
Shanghai Jiao Tong University · CNTechnical University of Munich · DEUniversity of Bern · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop a weakly supervised deep learning (WSDL) method that could utilize incomplete/missing survival data to predict the prognosis of extranodal natural killer/T cell lymphoma, nasal type (ENKTL) based on pretreatment

methodsOne hundred and sixty-seven patients with ENKTL who underwent pretreatment

resultsPSI achieved area under the curve scores of 0.9858 and 0.9946 (training set) and 0.8750 and 0.7344 (test set) in the prediction of progression-free survival (PFS) with the WSDL and CDL methods, respectively. PSI threshold of 1.0 could significantly differentiate the prognosis. In the test set, WSDL and CDL achieved prediction sensitivity, specificity, and accuracy of 87.50% and 62.50%, 83.33% and 83.33%, and 85.00% and 75.00%, respectively. Multivariate analysis confirmed PSI to be an independent significant predictor of PFS in both the methods.

conclusionThe WSDL-based framework was more effective for extracting

Indexed as

Deep LearningLymphoma, Extranodal NK-T-CellFluorodeoxyglucose F18HumansKiller Cells, NaturalPositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesFluorodeoxyglucose F1818F-FDG PET/CTDeep learningExtranodal natural killer/T cell lymphomaPrognosisProgression-free survival

Identifiers

PMID33611614
PMCPMC7896833
OpenAlexW3129732569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.