Evidence map›Paper›PMID 33611523›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2021

Improving the delivery of palliative care through predictive modeling and healthcare informatics.

Dennis H Murphree, Patrick M Wilson, Shusaku W Asai, Daniel J Quest, Yaxiong Lin, Piyush Mukherjee, Nirmal Chhugani, Jacob J Strand, Gabriel Demuth, David Mead and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Dennis H MurphreeDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-7800-455X
Patrick M WilsonDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Shusaku W AsaiDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Daniel J QuestInformation Technology, Mayo Clinic, Rochester, Minnesota, USA.
Yaxiong LinInformation Technology, Mayo Clinic, Rochester, Minnesota, USA.
Piyush MukherjeeInformation Technology, Mayo Clinic, Rochester, Minnesota, USA.
Nirmal ChhuganiInformation Technology, Mayo Clinic, Rochester, Minnesota, USA.
Jacob J StrandDivision of Palliative Care, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Gabriel DemuthDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
David MeadInformation Technology, Mayo Clinic, Rochester, Minnesota, USA.
Brian WrightInformation Technology, Mayo Clinic, Rochester, Minnesota, USA.
Andrew HarrisonDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
Jalal SoleimaniDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
Vitaly HerasevichDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
Brian W PickeringDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
Curtis B StorlieDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · USMayo Clinic in Florida · USMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAccess to palliative care (PC) is important for many patients with uncontrolled symptom burden from serious or complex illness. However, many patients who could benefit from PC do not receive it early enough or at all. We sought to address this problem by building a predictive model into a comprehensive clinical framework with the aims to (i) identify in-hospital patients likely to benefit from a PC consult, and (ii) intervene on such patients by contacting their care team. MATERIALS AND

methodsElectronic health record data for 68 349 inpatient encounters in 2017 at a large hospital were used to train a model to predict the need for PC consult. This model was published as a web service, connected to institutional data pipelines, and consumed by a downstream display application monitored by the PC team. For those patients that the PC team deems appropriate, a team member then contacts the patient's corresponding care team.

resultsTraining performance AUC based on a 20% holdout validation set was 0.90. The most influential variables were previous palliative care, hospital unit, Albumin, Troponin, and metastatic cancer. The model has been successfully integrated into the clinical workflow making real-time predictions on hundreds of patients per day. The model had an "in-production" AUC of 0.91. A clinical trial is currently underway to assess the effect on clinical outcomes.

conclusionsA machine learning model can effectively predict the need for an inpatient PC consult and has been successfully integrated into practice to refer new patients to PC.

Indexed as

Machine LearningMedical InformaticsPalliative CareAgedArea Under CurveDecision Support Systems, ClinicalDelivery of Health CareElectronic Health RecordsFemaleHumansMaleMiddle AgedQuality ImprovementROC Curveclinicaldecision support systemsmachine learningpalliative careprecision medicine

Identifiers

PMID33611523
PMCPMC8661428
OpenAlexW3133150084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.