Evidence map›Paper›PMID 33610705›Full record

ArticleJournal of ethnopharmacology2021

Self-treatment and adverse reactions with herbal products for treating symptoms associated with anxiety and depression in adults from the central-western region of Mexico during the Covid-19 pandemic.

Angel Josabad Alonso-Castro, Alan Joel Ruiz-Padilla, Miriam Ortiz-Cortes, Eleazar Carranza, Marco Antonio Ramírez-Morales, Raymundo Escutia-Gutiérrez, Yeniley Ruiz-Noa, Juan Ramon Zapata-Morales

Open access · greenAbstract read
In one paragraph

Article in Journal of ethnopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Insufficient Evidence to RecommendNeuropsychiatric disease and treatment · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Angel Josabad Alonso-CastroDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, Mexico. Electronic address: angeljosabad@ugto.mx.
Alan Joel Ruiz-PadillaDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, Mexico.
Miriam Ortiz-CortesDoctorado Interinstitucional en Arte y Cultura, Universidad Autónoma de Aguascalientes, Aguascalientes, Aguascalientes, Mexico.
Eleazar CarranzaInstituto de Investigación de Zonas Desérticas, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, Mexico.
Marco Antonio Ramírez-MoralesDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, Mexico.
Raymundo Escutia-GutiérrezDepartamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierias, Universidad de Guadalajara, Guadadalajara, Jalisco, Mexico.
Yeniley Ruiz-NoaDepartamento de Ciencias Médicas, División de Ciencias de La Salud, Universidad de Guanajuato, León, Guanajuato, Mexico.
Juan Ramon Zapata-MoralesDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, Mexico.
Universidad de Guanajuato · MXAutonomous University of Aguascalientes · MXAutonomous University of San Luis Potosí · MXUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ethnopharmacological relevanceThere are plant species used in the Mexican traditional medicine for the empirical treatment of anxiety and depression. AIM OF THE STUDY: This work assessed the prevalence of self-medication with medicinal plants and the prevalence of the concomitant use of prescribed psychiatric drugs and medicinal plants for treating symptoms associated with anxiety and depression during the Covid-19 lockdown in Mexico. MATERIALS AND

methodsThe suspected adverse reactions associated with drug-herb interactions were assessed. The factors associated with self-medication, the concomitant use of herb-drug combinations, and the presence of adverse reactions due their combined use is also reported. The study was descriptive and cross-sectional using an online questionnaire conducted among population with symptoms associated with anxiety and depression (n = 2100) from seven states of central-western Mexico.

resultsThe prevalence of the use of herbs (61.9%) and the concomitant use of drug-herb combinations (25.3%) were associated with being diagnosed with mental illness [OR:2.195 (1.655-2.912)] and the use of psychiatric medications [OR:307.994 (178.609-531.107)], respectively. The presence of adverse reactions (n = 104) by the concomitant use of drug-herb combinations was associated with being unemployed [p = 0.004, OR: 3.017 (1.404-6.486)].

conclusionHealth professionals should be aware if their patients concomitantly use medicinal plants and psychiatric drugs. Public health campaigns should promote the possible adverse reactions that might produce the concomitant use of drug-herb combinations for mental illnesses.

Indexed as

PandemicsAdolescentAdultAgedAnxietyCommunicable Disease ControlCOVID-19Cross-Sectional StudiesDepressionDrug InteractionsFemaleHumansMaleMental DisordersMexicoMiddle AgedPlant PreparationsPsychotropic DrugsAnxietyDepressionHerbal productsSelf-medication

Identifiers

PMID33610705
PMCPMC9387533
OpenAlexW3129348709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.