Evidence map›Paper›PMID 33610272›Full record

ReviewSeminars in radiation oncology2021

Personal and Prognostic: Tissue and Liquid Biomarkers of Radiotherapeutic Response in Non-Small Cell Lung Cancer.

Samuel R Jean-Baptiste, Steven J Feigenberg, Jay F Dorsey, Gary D Kao

Abstract readReview
In one paragraph

Review in Seminars in radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel R Jean-BaptisteDepartment of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Steven J FeigenbergDepartment of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Jay F DorseyDepartment of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address: jay.dorsey2@pennmedicine.upenn.edu.
Gary D KaoDepartment of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address: gary.kao@pennmedicine.upenn.edu.

Funding

Circulating Tumor Cells Analyses and Molecular Profiling for Patients Receiving Radiation TherapyR01CA201071 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DORSEY, JAY FITZGERALD, KAO, GARY D · 2016 to 2020
$2.2M
NCI NIH HHS R01 CA201071
6 · The paper itself

Abstract

Recent treatment advances have improved outcomes for patients with non-small cell lung cancer (NSCLC), often utilizing tumor molecular characterization to identify targetable mutations. This is further enhanced by advancements in "liquid biopsies", using peripheral blood for noninvasive, serial sampling of tumor biology. While tumor genomic alterations have established therapeutic implications in metastatic NSCLC, research is also ongoing to develop applications for tissue and liquid biomarkers in earlier stage disease, such as patients treated with radiation for early stage or locoregional NSCLC.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsBiomarkers, TumorHumansMutationPrognosisBiomarkers, Tumor

Identifiers

PMID33610272
PMCPMC9889131

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.