Evidence map›Paper›PMID 33610239›Full record

SynthesisIndian journal of medical microbiology2021

Clinical, epidemiological, laboratory, and radiological characteristics of novel Coronavirus (2019-nCoV) in retrospective studies: A systemic review and meta-analysis.

Ebrahim Kouhsari, Khalil Azizian, Mohammad Sholeh, Mohammad Shayestehpour, Marzieh Hashemian, Somayeh Karamollahi, Sajad Yaghoubi, Nourkhoda Sadeghiifard

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Indian journal of medical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The impact of coronavirus SARS-CoV-2 (COVID-19) in water: potential risks.Environmental science and pollution research international · 2021
    Review
  6. The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Ebrahim KouhsariClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran; Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Khalil AzizianDepartment of Lab Science, Sirjan School of Medical Sciences, Sirjan, Iran.
Mohammad SholehDepartment of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mohammad ShayestehpourDepartment of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran; Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Marzieh HashemianClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Somayeh KaramollahiClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Sajad YaghoubiDepartment of Clinical Microbiology, Iranshahr University of Medical Sciences, Iranshahr, Iran. Electronic address: sajadyaghuby@gmail.com.
Nourkhoda SadeghiifardClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran. Electronic address: Sadeghiifard@gmail.com.
Medical University of Ilam · IRIlam University · IRIranshahr University · IRIran University of Medical Sciences · IRKashan University of Medical Sciences · IRSirjan University of Technology · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn December 2019, a novel pneumonia related to the 2019 coronavirus unexpectedly developed in Wuhan, China. We aimed to review data of the novel Coronavirus (2019-nCoV) by analyzing all the published retrospective studies on the clinical, epidemiological, laboratory, and radiological characteristics of patients with 2019-nCoV.

methodsWe searched in four bibliographic databases PubMed, Scopus, Embase, and Web of Science) for studies March 10, 2020 focused on the clinical, epidemiological, laboratory, and radiological characteristics of patients with 2019-nCoV for meta-analysis. The Newcastle-Ottawa Scale was used to quality assessment, and publication bias was analyzed by Egger's test. In the meta-analysis, a random-effects model with Stata/SE software, v.14.1 (StataCorp, College Station, TX) was used to obtain a pooled incidence rate.

resultsFifty studies were included in this systematic review and meta-analysis with 8815 patients and the mean age was 46 years and 4647 (52.7%) were male. The pooled incidences rate of clinical symptoms were: fever (83%, 95% CI: 0.77, 0.89), cough (59%, 95% CI: 0.48, 0.69), myalgia or fatigue (31%, 95% CI: 0.23, 0.39), sputum production (29%, 95% CI: 0.21, 0.39), and dyspnea (19%, 95% CI: 0.12, 0.26). The pooled incidence rate of acute respiratory distress syndrome (ARDS) was (22%, 95% CI: 0.00, 0.60).

conclusionThe results of this systemic review and meta-analysis present a quantitative pooled incidence rate of different characters of 2019-nCoV and has great potential to develop diagnosis and patient's stratification in 2019-nCoV. However, this conclusions of this study still requisite to be warranted by more careful design, larger sample size multivariate studies to corroborate the results of this meta-analysis.

Indexed as

SARS-CoV-2AdultAgedCOVID-19Disease ManagementFemaleGlobal HealthHumansMaleMiddle AgedPublication BiasPublic Health SurveillanceRadiographyRetrospective StudiesSymptom Assessment2019-nCoVClinicalEpidemiologicalLaboratory, and radiological characteristicsMeta-analysis

Identifiers

PMID33610239
PMCPMC7667392
OpenAlexW3108305337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.