Evidence map›Paper›PMID 33610095›Full record

ArticleDrug and alcohol dependence2021

Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.

Dennis P Watson, Tess Weathers, Alan McGuire, Alex Cohen, Philip Huynh, Clay Bowes, Daniel O'Donnell, Krista Brucker, Sumedha Gupta

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07119658 (Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07119658 nacompletednot on this mapstarted 2025, after this paper: background citation

Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial

TypeinterventionalSponsorIndiana UniversityRan2025 to 2026Enrolled20ConditionsHypertension, Hyperglycemia, Dyslipidemia, Metabolic SyndromeArmsComposite intervention to address MetS
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Navigating Substance Use Care in the Emergency Department: A Scoping Review.Journal of the American College of Emergency Physicians open · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Peer support for patients with opioid use disorder in the emergency department: A narrative review.Journal of the American College of Emergency Physicians open · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Dennis P WatsonChestnut Health Systems, Lighthouse Institute, 221 W. Walton St., Chicago, IL, 60610, United States. Electronic address: dpwatson@chestnut.org.
Tess WeathersIndiana University Richard M. Fairbanks School of Public Health, Department of Social and Behavioral Sciences, 1050 Wishard Blvd., Indianapolis, IN, 46202, United States. Electronic address: tweather@iu.edu.
Alan McGuireRichard L. Roudebush VAMC, Health Services Research and Development, 1481 W. 10th St (11H) Rm. C8108, Indianapolis, IN, 46202, United States; Indiana University Purdue University Indianapolis, Department of Psychology, 402 N. Blackford St., Indianapolis, IN, 46202, United States. Electronic address: alan.mcguire@va.gov.
Alex CohenGiveWell, 1714 Franklin Street, Oakland, CA, 94612, United States. Electronic address: alexwcohen@gmail.com.
Philip HuynhWayne State University, School of Social Work, Center for Behavioral Health and Justice, 5201 Cass Avenue Suite 226, Detroit, MI, 48202, United States. Electronic address: philip.huynh@wayne.edu.
Clay BowesIndiana University School of Medicine, 340 W. 10th St., Indianapolis, IN, 46202, United States. Electronic address: claybowe@iu.edu.
Daniel O'DonnellIndiana University School of Medicine, Department of Emergency Medicine, 720 Eskenazi Ave., Indianapolis, IN, 46202, United States. Electronic address: dapodonn@iu.edu.
Krista BruckerSB Emergency Physicians, South Bend, IN, United States. Electronic address: kbrucker@gmail.com.
Sumedha GuptaDepartment of Economics, Indiana University Purdue University Indianapolis, United States. Electronic address: sugupta@iu.edu.
Indiana University School of MedicineAlexza Pharmaceuticals (United States) · USChestnut Health Systems · USHealth Services Research & Development · USRichard M. Fairbanks Foundation · USSouth Bend Museum of Art · USUniversity of Indianapolis · USWayne State University · US

Funding

The Indiana EMergency Care REsearch (Indiana EMCARE) training program at Indiana University School ofMedicine (IUSM)K12HL133310 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI KROENKE, KURT · 2016 to 2020
$3.0M
NHLBI NIH HHS K12 HL133310
6 · The paper itself

Abstract

backgroundIn recent years, a number of emergency department (ED)-based interventions have been developed to provide supports and/or treatment linkage for people who use opioids. However, there is limited research supporting the effectiveness of the majority of these interventions. Project POINT is an ED-based intervention aimed at providing opioid overdose survivors with naloxone and recovery supports and connecting them to evidence-based medications for opioid use disorder (MOUD). An evaluation of POINT was conducted.

methodsA difference-in-difference analysis of electronic health record data was completed to understand the difference in outcomes for patients admitted to the ED when a POINT staff member was working versus times when they were not. The observation window was January 1, 2012 to July 6, 2019, which included N = 1462 unique individuals, of which 802 were in the POINT arm. Outcomes of focus include MOUD opioid prescriptions dispensed, active non-MOUD opioid prescriptions dispensed, naloxone access, and drug poisonings.

resultsThe POINT arm had a significant increase in MOUD prescriptions dispensed, non-MOUD prescriptions dispensed, and naloxone access (all p-values < 0.001). There was no significant effect related to subsequent drug poisoning-related hospital admissions.

conclusionsThe results support the assertion that POINT is meeting its two primary goals related to increasing naloxone access and connecting patients to MOUD. Generalization of these results is limited; however, the evaluation contributes to a nascent area of research and can serve a foundation for future work.

Indexed as

Electronic Health RecordsOpiate OverdoseAdultAnalgesics, OpioidDrug OverdoseDrug PrescriptionsEmergency Medical ServicesEmergency Service, HospitalFemaleHospitalizationHumansMaleMiddle AgedNaloxoneOpioid-Related DisordersSurvivorsAnalgesics, OpioidNaloxoneDifference-in-differenceEmergency medicineEvaluationMedication for opioid use disorderNaloxoneOpioid use disorderOverdosePeer recovery coaching

Identifiers

PMID33610095
PMCPMC8026710
OpenAlexW3129275396

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.