Observational studyBJS open2021
Perforation rate after a diagnosis of uncomplicated appendicitis on CT.
Observational study in BJS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Impact of the COVID-19 pandemic on the pattern of acute appendicitis, a single-center study.Frontiers in surgery · 2026Article
- Complicated versus uncomplicated acute appendicitis: clinical characteristics, diagnostic scores, surgical management, and outcomes in a tertiary hospital in Mogadishu, Somalia.Frontiers in surgery · 2026Article
- Dharma: A novel, clinically grounded machine learning framework for pediatric appendicitis-Diagnosis, severity assessment and evidence-based clinical decision support.PLOS digital health · 2026Article
- C-Reactive Protein, International Normalized Ratio, and Fibrinogen in Diagnostic Scale of Complicated Acute Appendicitis.Clinics and practice · 2025Article
- Pre-hospital management and patient-related factors affecting access to the surgical care of appendicitis - a survey study.Scandinavian journal of primary health care · 2024Article
- Complicated appendicitis increases the hospital length of stay.Surgery open science · 2022Article
- Characteristics of Patients Presented with Complicated Appendicitis in Adama, Ethiopia: A Cross-Sectional Study.Open access emergency medicine : OAEM · 2022Article
- Article
- Appendiceal adenocarcinoma found by surgery for acute appendicitis is associated with older age.BMC surgery · 2021Article
- Appendicectomy for Uncomplicated Simple Appendicitis: Is It Always Required?Surgery research and practice · 2021Article
- External Validation of Adult Prediction Models for Complicated Appendicitis After Contrast-Enhanced Computed Tomography: A Single-Centre Study.ANZ journal of surgeryArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppendicectomy is a common emergency operation. The aim of this analysis was to study the effect of preoperative delay on disease progression, and whether a novel scoring system (Atema score) could be useful in predicting complicated appendicitis.
methodsPatients with uncomplicated acute appendicitis on CT and who underwent appendicectomy in 2014-2015 were analysed for patient characteristics, preoperative delay and outcomes.
resultsOf 837 patients with uncomplicated appendicitis on CT, 187 (22.3 per cent) were found to have complicated appendicitis at surgery. The median time estimate for perforation was 25.4 h after CT, with an hourly rate of perforation of 2 per cent. Patients with an Atema score of 6 or less and those with no appendicolith on CT and a C-reactive protein level below 51 mg/l were the slowest to develop perforation, reaching a perforation rate of 5 per cent in 7.1 and 7.6 h respectively.
conclusionA substantial proportion of patients with uncomplicated acute appendicitis on CT have complicated appendicitis at surgery. However, in patients with no risk factors, surgery can be postponed safely for up to 7 h.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.