Evidence map›Paper›PMID 33609316›Full record

ReviewAnnals of the New York Academy of Sciences2022

Enhancing cardiac arrest survival with extracorporeal cardiopulmonary resuscitation: insights into the process of death.

Tom P Aufderheide, Rajat Kalra, Marinos Kosmopoulos, Jason A Bartos, Demetris Yannopoulos

Open access · greenAbstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tom P AufderheideDepartment of Emergency Medicine, HUB for Collaborative Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Rajat KalraCenter for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.
Marinos KosmopoulosCenter for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.
Jason A BartosCenter for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.
Demetris YannopoulosCenter for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.
University of Minnesota Medical Center · USMedical College of Wisconsin · USUniversity of Minnesota System · US

Funding

Advanced REperfusion STrategies- The ARREST TrialR33HL142696 · NHLBI · UNIVERSITY OF MINNESOTA · PI AUFDERHEIDE, TOM PAUL, YANNOPOULOS, DEMETRIS · 2019 to 2020
$1.3M
Advanced REperfusion STrategies- The ARREST TrialR61HL142696 · NHLBI · UNIVERSITY OF MINNESOTA · PI AUFDERHEIDE, TOM PAUL, YANNOPOULOS, DEMETRIS · 2018 to 2018
$750k
Leona M. and Harry B. Helmsley Charitable TrustNHLBI NIH HHS 4R33HL142696-02NHLBI NIH HHS R33 HL142696NHLBI NIH HHS R61 HL142696
6 · The paper itself

Abstract

Extracorporeal cardiopulmonary resuscitation (ECPR) is an emerging method of cardiopulmonary resuscitation to improve outcomes from cardiac arrest. This approach targets patients with out-of-hospital cardiac arrest previously unresponsive and refractory to standard treatment, combining approximately 1 h of standard CPR followed by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and coronary artery revascularization. Despite its relatively new emergence for the treatment of cardiac arrest, the approach is grounded in a vast body of preclinical and clinical data that demonstrate significantly improved survival and neurological outcomes despite unprecedented, prolonged periods of CPR. In this review, we detail the principles behind VA-ECMO-facilitated resuscitation, contemporary clinical approaches with outcomes, and address the emerging new understanding of the process of death and capability for neurological recovery.

Indexed as

BrainCardiopulmonary ResuscitationDeathExtracorporeal Membrane OxygenationHumansNervous System DiseasesOut-of-Hospital Cardiac ArrestSurvivalbrain deathcardiopulmonary resuscitationextracorporeal cardiopulmonary resuscitationextracorporeal membrane oxygenationneurological prognosticationneurological recovery

Identifiers

PMID33609316
PMCPMC8377067
OpenAlexW3131177147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.