ArticleAllergy2021
Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multi-national cohort.
Article in Allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Pediatric asthma control during the COVID-19 pandemic: A systematic review and meta-analysis.Pediatric pulmonology · 2022Pooled it
- SQ House Dust Mite Sublingual Immunotherapy Tablet in Children With Allergic Asthma: A Randomised Phase III Trial.Allergy · 2025Trial
- [Efficacy and safety of dust mite subcutaneous immunotherapy in children with allergic asthma： a prospective randomized controlled study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Trial
- Exploring the Potential Benefits of Biologic Therapies Beyond Respiratory Allergy.ImmunoTargets and therapy · 2026Review
- Factors associated with asthma attack recurrence in Ecuadorian children: longitudinal study of potential impact of the COVID-19 pandemic lockdown.BMJ open respiratory research · 2025Article
- Impact of COVID-19 pandemic on childhood asthma and wheezing disorders.World journal of pediatrics : WJP · 2025Article
- Early Origins of Asthma and Allergies: Clues From Studies in China.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Review
- Review
- The COVID-19 pandemic and asthma management: a family caregiver perspective.The Journal of asthma : official journal of the Association for the Care of Asthma · 2025Article
- Preschool Asthma Children: Navigating COVID-19's Impact on Treatment Adherence.Turkish archives of pediatrics · 2025Article
- Associations of aeroallergen testing with reduced oral corticosteroid bursts among adults with asthma.The journal of allergy and clinical immunology. Global · 2025Article
- Retrospective Study of the Impact of SARS-CoV-2 Infection on Asthma Control in Children.Journal of clinical medicine · 2025Article
- Features of children with critical asthma hospitalized in a pediatric intensive care unit: Results from the ICU-3A study.Pediatric pulmonology · 2025Article
- Global change, climate change, and asthma in children: Direct and indirect effects - A WAO Pediatric Asthma Committee Report.The World Allergy Organization journal · 2024Review
- National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022.Scientific reports · 2024Article
- Pediatric asthma comorbidities: Global impact and unmet needs.The World Allergy Organization journal · 2024Review
- Assessing severity of COVID-19 and the development of multi system inflammatory syndrome in children (MIS-C) in pediatric patients with atopic disease.Allergy and asthma proceedings · 2024Article
- Article
- Prediction of Asthma Exacerbations in Children.Journal of personalized medicine · 2023Review
- Incidence and causative agent distribution of viral-induced paediatric asthma exacerbations under strict infection control measures: a single-centre retrospective study in Japan.BMC pulmonary medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
43 authors at 20 institutions in 17 countries.
Funding
Abstract
backgroundThe interplay between COVID-19 pandemic and asthma in children is still unclear. We evaluated the impact of COVID-19 pandemic on childhood asthma outcomes.
methodsThe PeARL multinational cohort included 1,054 children with asthma and 505 non-asthmatic children aged between 4 and 18 years from 25 pediatric departments, from 15 countries globally. We compared the frequency of acute respiratory and febrile presentations during the first wave of the COVID-19 pandemic between groups and with data available from the previous year. In children with asthma, we also compared current and historical disease control.
resultsDuring the pandemic, children with asthma experienced fewer upper respiratory tract infections, episodes of pyrexia, emergency visits, hospital admissions, asthma attacks, and hospitalizations due to asthma, in comparison with the preceding year. Sixty-six percent of asthmatic children had improved asthma control while in 33% the improvement exceeded the minimal clinically important difference. Pre-bronchodilatation FEV
conclusionChildhood asthma outcomes, including control, were improved during the first wave of the COVID-19 pandemic, probably because of reduced exposure to asthma triggers and increased treatment adherence. The decreased frequency of acute episodes does not support the notion that childhood asthma may be a risk factor for COVID-19. Furthermore, the potential for improving childhood asthma outcomes through environmental control becomes apparent.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.