Evidence map›Paper›PMID 33608916›Full record

ArticleClinical transplantation2021

Heart transplantation in the UK during the first wave of the SARS-CoV-2 pandemic.

Gillian Hardman, Ruth Sutcliffe, Rachel Hogg, Lisa Mumford, Laura Grocott, Lorraine Jerrett, Sarah-Jane Mead-Regan, Jane Nuttall, Stephanie Dunn, Philip Seeley and 7 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

Gillian HardmanClinical Research and Clinical Audit Fellow in Cardiothoracic Transplantation, NHS Blood and Transplant, Bristol, UK.ORCID 0000-0001-9600-4097
Ruth SutcliffeAllied Health Professional representative, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Rachel HoggStatistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Lisa MumfordStatistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Laura GrocottHeart and Lung transplant recipient coordinator, Queen Elizabeth Hospital, Birmingham, UK.
Lorraine JerrettHeart transplant recipient coordinator, Golden Jubilee Hospital, Glasgow, UK.
Sarah-Jane Mead-ReganHeart and Lung transplant recipient coordinator, Great Ormond Street Hospital for Children, London, UK.
Jane NuttallRecipient transplant coordinator, Wythenshawe hospital, Manchester, UK.
Stephanie DunnHeart and Lung transplant recipient coordinator, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Philip SeeleyLead Nurse for Heart and Lung Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Richard QuigleyLead Nurse for transplantation, Royal Papworth Hospital, Cambridge, UK.
Johnathan R DalzellConsultant cardiologist and clinical lead, Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, UK.
Nawwar Al-AttarChair, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Jayan ParameshwarChair Cardiothoracic Advisory Group, NHS Blood and Transplant, Bristol, UK.
Andrew J FisherInstitute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Karen BoothInstitute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
John H DarkNewcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
NHS Blood and Transplant · GBFreeman Hospital · GBGolden Jubilee National Hospital · GBGreat Ormond Street Hospital · GBJubilee Hospital · GBNewcastle University · GBPapworth Hospital · GBQueen Elizabeth Hospital Birmingham · GBWythenshawe Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aim to evaluate practice and understand the impact of the first wave of the SARS-CoV-2 pandemic on heart transplantation in the UK.

methodsA retrospective review of the UK Transplant Registry (UKTR) and a national survey of UK heart transplant centers have been performed. The early pandemic period is defined here as 1 March to 31 May 2020.

resultsThere was geographic variation in the prevalence of COVID-19 across the UK. All centers reported adaptations to maintain the safety of their staff, candidate, and recipient populations. The number of donors fell by 31% during the early pandemic period. Heart utilization increased to 35%, compared to 26% during the same period of 2019. The number of heart transplants was well maintained, across all centers, with 38 performed, compared to 41 during the same period of 2019, with no change in 30-day survival. Twenty-seven heart transplant recipients with confirmed COVID-19 infection were reported during the study period.

conclusionAll UK heart transplant centers have successfully adapted their programs to overcome the challenges of staff redeployment and ICU and hospital resource limitation, associated with the pandemic, whilst continuing heart transplant activity. On-going evaluation of practice changes, with sharing of lessons learned, is required as the pandemic continues.

Indexed as

COVID-19Heart TransplantationHumansPandemicsRetrospective StudiesSARS-CoV-2United KingdomCoronavirus pandemicCOVID-19Heart transplantationorgan donationSARS-CoV-2

Identifiers

PMID33608916
PMCPMC7995148
OpenAlexW3130313797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.