Evidence map›Paper›PMID 33608856›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022

Incremental value of epicardial fat volume to coronary artery calcium score and traditional risk factors for predicting myocardial ischemia in patients with suspected coronary artery disease.

Wenji Yu, Feifei Zhang, Bao Liu, Jianfeng Wang, Xiaoliang Shao, Min-Fu Yang, Xiaoyu Yang, Zhifang Wu, Sijin Li, Yunmei Shi and 3 more

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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  5. Machine learning to predict hemodynamically significant CAD based on traditional risk factors, coronary artery calcium and epicardial fat volume.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
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  12. Coronary artery calcium or epicardial fat: Different markers for different people.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Wenji YuDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Feifei ZhangDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Bao LiuDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Jianfeng WangDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Xiaoliang ShaoDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Min-Fu YangDepartment of Nuclear Medicine, Affiliated Beijing Chaoyang Hospital of Capital Medical University, Beijing, China.
Xiaoyu YangDepartment of Cardiology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Zhifang WuDepartment of Nuclear Medicine, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Sijin LiDepartment of Nuclear Medicine, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Yunmei ShiDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Bing WangDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Yiduo XuDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Yuetao WangDepartment of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China. yuetao-w@163.com.ORCID 0000-0003-2507-6012
Soochow University · CNShanxi Medical University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpicardial fat volume (EFV) has been reported to be associated with coronary artery disease (CAD). CAD is the leading cause of myocardial ischemia and myocardial ischemia is closely related to major adverse cardiovascular events. We hypothesized that EFV could provide incremental value to traditional risk factors and coronary artery calcium score (CACS) in predicting myocardial ischemia in Chinese patients with suspected CAD.

methodsWe retrospectively studied 204 Chinese patients with suspected CAD who underwent single-photon emission computerized tomography-myocardial perfusion imaging (SPECT-MPI) combined with computed tomography (CT). Pericardial contours were manually defined, and EFV was automatically calculated. A reversible perfusion defect with summed difference score (SDS) ≥ 2 was defined as myocardial ischemia.

resultsThe myocardial ischemia group had higher EFV than normal MPI group (137.80 ± 34.95cm

conclusionsIn Chinese patients with suspected CAD, EFV was significantly associated with myocardial ischemia, and improved prediction of myocardial ischemia above traditional risk factors and CACS.

Indexed as

Coronary Artery DiseaseMyocardial IschemiaMyocardial Perfusion ImagingCalciumCoronary AngiographyHumansPredictive Value of TestsRetrospective StudiesRisk FactorsCalciumCACEFVMyocardial ischemiaNon-contrast CTSPECT-MPI

Identifiers

PMID33608856
OpenAlexW3133199135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.