ArticleJournal of assisted reproduction and genetics2021
Elective oocyte cryopreservation for age-related fertility decline.
Article in Journal of assisted reproduction and genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Association Between Human Embryo Culture Conditions, Cryopreservation, and the Potential Risk of Birth Defects in Children Conceived Through Assisted Reproduction Technology.Medicina (Kaunas, Lithuania) · 2025Review
- The role of heat shock protein 70 on oocyte apoptosis during vitrification.Open veterinary journal · 2025Review
- Global Mapping and Visualization Analysis of Almost Five Decades of Egg Freezing Research: Trends, Hotspots and Prospects.International journal of women's health · 2025Article
- Exploring awareness and attitudes toward oocyte cryopreservation among women of reproductive age.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Egg Cryopreservation for Social Reasons-A Literature Review.Healthcare (Basel, Switzerland) · 2024Review
- International attitudes towards medical and planned oocyte cryopreservation.Journal of assisted reproduction and genetics · 2024Article
- Balancing choice and socioeconomic realities: analyzing behavioral and economic factors in social oocyte cryopreservation decisions.Frontiers in endocrinology · 2024Article
- The first nationwide website survey of the availability and costs of medical and non-medical oocyte cryopreservation in Japan.Heliyon · 2023Article
- Can Cryopreservation in Assisted Reproductive Technology (ART) Induce Epigenetic Changes to Gametes and Embryos?Journal of clinical medicine · 2023Review
- Social egg freezing: Motivations, treatment experiences and the impact of Covid-19 - a single-center experience.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Effects of oocyte vitrification on gene expression in the liver and kidney tissues of adult offspring.Journal of assisted reproduction and genetics · 2022Article
- The effect of hematopoietic stem cell transplantation on fertility and strategies for improvement.Bone marrow transplantation · 2022Review
- How effective is digital educational content in shaping fertility awareness? An interventional, cross-sectional study.Journal of assisted reproduction and genetics · 2022Article
- Vitrification within a nanoliter volume: oocyte and embryo cryopreservation within a 3D photopolymerized device.Journal of assisted reproduction and genetics · 2022Article
- Oocyte Cryopreservation at a Young Age Provides an Effective Strategy for Expanding Fertile Lifespan.Frontiers in reproductive health · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWomen who pursue fertility at an advanced age are increasingly common. Family planning and sexual education have traditionally focused on contraception and prevention of sexually transmitted diseases. A focus should now also be placed on fertility awareness and fertility preservation. This manuscript aims to give an update on the existing evidence around elective oocyte cryopreservation, also highlighting the need for fertility education and evidence-based, individualized counselling.
methodsA thorough electronic search was performed from the start of databases to March 2020 aiming to summarize the existing evidence around elective egg freezing, the logic behind its use, patient counselling and education, success rates and risks involved, regulation, cost-effectiveness, current status and future perspectives.
resultsClinician-led counselling regarding reproductive aging and fertility preservation is often overlooked. Elective oocyte cryopreservation is not a guarantee of live birth, and the answer regarding cost-effectiveness needs to be individualized. The existing studies on obstetric and perinatal outcomes following the use of egg freezing are, until now, reassuring. Constant monitoring of short-term and long-term outcomes, uniform regulation and evidence-based, individualized counselling is of paramount importance.
conclusionsElective oocyte cryopreservation is one of the most controversial aspects of the world of assisted reproduction, and a lot of questions remain unanswered. However, women today do have this option which was not available in the past. Elective oocyte cryopreservation for age-related fertility decline should be incorporated in women's reproductive options to ensure informed decisions and reproductive autonomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.