SynthesisNeurosurgical review2021
The impact of preoperative anxiety on patients undergoing brain surgery: a systematic review.
Synthesis in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Recognizing the psychological impact of a glioma diagnosis on mental and behavioral health: a systematic review of what neurosurgeons need to know.Journal of neurosurgery · 2023Pooled it
- Social support and pre-operative anxiety in patients undergoing elective surgical procedures: A systematic review and meta-analysis.Journal of health psychology · 2023Pooled it
- Effects of dexmedetomidine nasal spray on perioperative anxiety and quality of postoperative recovery in patients undergoing modified radical mastectomy for breast cancer.Frontiers in medicine · 2026Trial
- Virtual Reality-Based Intervention to Reduce Preoperative Anxiety in Adults Undergoing Elective Surgery: A Randomized Clinical Trial.JAMA network open · 2023Trial
- Preoperative anxiety among cardiac surgery patients and its impact on major adverse cardiac events and mortality- A randomized, parallel-group study.Annals of cardiac anaesthesiaTrial
- Effects of immersive virtual reality and non-immersive video distraction on preoperative anxiety in patients undergoing elective abdominal surgery: a three-arm randomised controlled trial.Surgical endoscopy · 2026Article
- Personalized Perioperative Music Listening: A Human-Centered Approach to Precision Anesthesia.Cureus · 2026Review
- The psychological impact of using 3D printing and imaging technology for patient education: a scoping review.3D printing in medicine · 2026Review
- The impact of preoperative regular exercise on mental health in patients undergoing Type II incision surgery.Perioperative medicine (London, England) · 2026Article
- Article
- Preliminary Usability Assessment of a Rule-Based Digital Self-Monitoring Platform for Patients With Brain Tumors Toward Digital Early Warning Systems: Pilot Feasibility Study.JMIR formative research · 2026Article
- Music During Awake Brain Tumor Resection: A Case Series.Journal of neurosurgical anesthesiology · 2026Article
- Article
- Unlocking patient insights: a prospective study on patient reported outcome measures in thoracic surgery.Journal of cardiothoracic surgery · 2026Observational
- Effect of repetitive transcranial magnetic stimulation on perioperative anxiety in female patients: study protocol for a single-center, randomized controlled study.Frontiers in medicine · 2026Article
- Measuring health literacy among older inpatients after elective surgery: evaluation of the European Health Literacy Survey Questionnaire-short form (HLS-EU-Q16).Frontiers in psychology · 2026Article
- Preoperative anxiety in patients undergoing minimally invasive thoracic surgery: A prospective study of predictors and Patient-Reported concerns.Scientific reports · 2025Article
- Decoding Fear: Analysis and Prognosis of Preoperatory Stress Level Through Advanced Statistical Modelling-A Prospective Study Across Multiple Surgical Specialties.Medical sciences (Basel, Switzerland) · 2025Article
- Anxiety and self-efficacy in Chinese lung cancer patients: cross-lagged effects and the mediation of resilience.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Development and Validation of a Large Language Model-Powered Chatbot for Neurosurgery: Mixed Methods Study on Enhancing Perioperative Patient Education.Journal of medical Internet research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preoperative anxiety is a common reaction exhibited by up to 80% of patients who are scheduled for surgical procedures and characterized by psychological and physical changes which may affect their perioperative period. Our aim is to report the most up-to-date evidence on preoperative anxiety in brain surgery patients through a systematic analysis of the studies produced in the last decades. We performed a systematic review of literature by searching PubMed, Embase, and Cochrane Library databases. Data were extracted using the Population, Intervention, Comparison, Outcome framework and critically analyzed. PRISMA guidelines were applied, and the risk of bias of the included studies was assessed using the Risk of bias (RoB) 2 and ROBINS tools, as was the methodological quality, following GRADE criteria. We included 27 articles, accounting for 2558 patients in twelve different countries. The prevalence of preoperative anxiety ranged from 17 up to 89%, higher in female patients. Preoperative anxiety was associated with lower quality of life and cognitive performance, higher need for information, poorer memory and attention, longer hospitalization, depressive symptoms, and increase of physical disability; no correlation with survival rate was found. Seven randomized controlled trials attested the efficacy of acupuncture, music therapy, virtual reality, and pharmacological support in lowering anxiety levels. Preoperative anxiety is a common phenomenon that could negatively affect the perioperative period of brain surgery patients: this is something that should not be neglected to achieve better care through early prevention and optimal management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.