Evidence map›Paper›PMID 33608827›Full record

ArticleProbiotics and antimicrobial proteins2021

Bacillus Toyonensis BCT-7112

Francisco Denis Souza Santos, Lucas Reichert Maubrigades, Vitória Sequeira Gonçalves, Helen Cabaldi Franz, Paulo Ricardo Centeno Rodrigues, Rodrigo Casquero Cunha, Fábio Pereira Leivas Leite

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Plants (Basel, Switzerland) · 2026
    Review
  2. Journal of fungi (Basel, Switzerland) · 2025
    Article
  3. The Bacterial Spore as a Mucosal Vaccine Delivery System.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Francisco Denis Souza SantosBiotechnology Department, Center for Technological Development, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil.
Lucas Reichert MaubrigadesBiotechnology Department, Center for Technological Development, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil.
Vitória Sequeira GonçalvesBiotechnology Department, Center for Technological Development, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil.
Helen Cabaldi FranzVeterinary School, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil.
Paulo Ricardo Centeno RodriguesVeterinary School, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil.
Rodrigo Casquero CunhaBiotechnology Department, Center for Technological Development, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil.
Fábio Pereira Leivas LeiteBiotechnology Department, Center for Technological Development, Federal University of Pelotas, Capão do Leão, Rio Grande do Sul, 96160-900, Brazil. fleivasleite@gmail.com.ORCID 0000-0003-0941-7286
Universidade Federal de Pelotas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial spores of the genus Bacillus are being evaluated as adjuvant molecules capable of improving the immune response to vaccines. In this study, we investigate whether subcutaneously administered spores of B. toyonensis BCT-7112

Indexed as

Adjuvants, ImmunologicBacillusAnimalsDisease Models, AnimalHerpesviridae InfectionsHerpesvirus 5, BovineInterleukin-12Interleukin-4MiceOligopeptidesSpores, BacterialViral VaccinesAdjuvants, ImmunologicInterleukin-12Interleukin-4OligopeptidesViral VaccinesBacillusCytokinesImmunomodulationSporeVaccine

Identifiers

PMID33608827
OpenAlexW3131878735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.