Evidence map›Paper›PMID 33608745›Full record

ArticleSurgery today2021

Optimal treatment and complications of patients with the perforated upper gastrointestinal tract.

Takahito Sugase, Toshiya Michiura, Shoichiro Urabe, Kazuki Sasaki, Nobuyasu Hayashi, Kazuo Yamabe

Abstract read
PubMed Publisher
In one paragraph

Article in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. A rare case of idiopathic gastric rupture in an elderly female.Clinical journal of gastroenterology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Takahito SugaseDepartment of Surgery, Kinan Hospital, 46-70 Shinjo, Tanabe, Wakayama, 646-8588, Japan. getssugase0130@gmail.com.
Toshiya MichiuraDepartment of Surgery, Kinan Hospital, 46-70 Shinjo, Tanabe, Wakayama, 646-8588, Japan.
Shoichiro UrabeDepartment of Surgery, Kinan Hospital, 46-70 Shinjo, Tanabe, Wakayama, 646-8588, Japan.
Kazuki SasakiDepartment of Surgery, Kinan Hospital, 46-70 Shinjo, Tanabe, Wakayama, 646-8588, Japan.
Nobuyasu HayashiDepartment of Surgery, Kinan Hospital, 46-70 Shinjo, Tanabe, Wakayama, 646-8588, Japan.
Kazuo YamabeDepartment of Surgery, Kinan Hospital, 46-70 Shinjo, Tanabe, Wakayama, 646-8588, Japan.
Kinan Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe perforation of the upper gastrointestinal tract is still associated with a high risk of complications and mortality. We aimed to evaluate the optimal treatment and post-treatment complications for this condition.

methodsThis was a retrospective, single-center study conducted between 2010 and 2019. We analyzed 50 patients with intraperitoneal free air caused by peptic ulcer (44 cases) or cancer (six cases).

resultsAll patients initially received either conservative therapy (n = 7) or surgery (n = 43). The nonsurgically cured patients were significantly younger and had mild peritonitis and also had a shorter hospital stay. Two patients were converted to surgery due to worsening symptoms, and one of them was elderly and had a long perforation-to-treatment time. Regarding postoperative complications, patients with Grade II-V (n = 21) were significantly older and had a poorer physical status, longer perforation-to-surgery time, and higher preoperative CRP and lactate than those with Grade 0-I (n = 24). Multivariable analyses identified elevated preoperative lactate as an independent risk factor for postoperative complications. The patients with noncurative surgery for perforated advanced gastric cancer all died within 1 year after surgery.

conclusionsConsideration should be given to the nonsurgical indications in elderly and delayed treatment patients and the postoperative outcomes of patients with preoperatively elevated lactate levels.

Indexed as

Conservative TreatmentAdultAgedAge FactorsBiomarkersConversion to Open SurgeryDigestive System Surgical ProceduresFemaleHumansIntestinal PerforationLactatesMaleMiddle AgedPeptic UlcerPostoperative ComplicationsRetrospective StudiesBiomarkersLactatesConservative therapyGastric cancerPeptic ulcerPerforated upper gastrointestinal tractPostoperative complications

Identifiers

PMID33608745
OpenAlexW3131136972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.