ArticleScientific reports2021
Imaging atelectrauma in Ventilator-Induced Lung Injury using 4D X-ray microscopy.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Evolution of hierarchical phase-contrast tomography on the European Synchrotron beamlines BM05 and BM18: a whole adult human brain imaging case study.Journal of synchrotron radiation · 2026Article
- Power, Duration, and Compliance: Reframing Risk of Ventilatory-Induced Lung Injury With the Risk-Adjusted Mechanical-Power Score.Critical care medicine · 2026Article
- Injury Mechanics in Surfactant-Depleted and Healthy Rat Lungs: A Multi-scale Consideration of Artificial and Physiological Ventilation.Annals of biomedical engineering · 2026Article
- The lung in acute respiratory failure: insights from synchrotron radiation imaging.Intensive care medicine experimental · 2026Review
- In vivo imaging of central nervous system fluid spaces using synchrotron radiation-based micro computed tomography.Nature communications · 2026Article
- Dynamic laboratory x-ray phase-contrast microtomography with structure-based prior regularisation.Measurement science & technology · 2025Article
- Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury.Scientific reports · 2025Article
- Regional ventilation dynamics of electrical impedance tomography validated with four-dimensional computed tomography: single-center, prospective, observational study.Critical care (London, England) · 2024Observational
- Optimising 4D imaging of fast-oscillating structures using X-ray microtomography with retrospective gating.Scientific reports · 2024Article
- High resolution propagation-based lung imaging at clinically relevant X-ray dose levels.Scientific reports · 2023Article
- Deep 3D reconstruction of synchrotron X-ray computed tomography for intact lungs.Scientific reports · 2023Article
- Assessment of Heterogeneity in Lung Structure and Function During Mechanical Ventilation: A Review of Methodologies.Journal of engineering and science in medical diagnostics and therapy · 2022Review
- Computational lung modelling in respiratory medicine.Journal of the Royal Society, Interface · 2022Review
- Lung tissue biomechanics imaged with synchrotron phase contrast microtomography in live rats.Scientific reports · 2022Article
- Imaging Regional Lung Structure and Function in Small Animals Using Synchrotron Radiation Phase-Contrast and K-Edge Subtraction Computed Tomography.Frontiers in physiology · 2022Review
- Biological effects of COVID-19 on lung cancer: Can we drive our decisions.Frontiers in oncology · 2022Review
- Effects of Lung Injury on Regional Aeration and Expiratory Time Constants: Insights From Four-Dimensional Computed Tomography Image Registration.Frontiers in physiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanical ventilation can damage the lungs, a condition called Ventilator-Induced Lung Injury (VILI). However, the mechanisms leading to VILI at the microscopic scale remain poorly understood. Here we investigated the within-tidal dynamics of cyclic recruitment/derecruitment (R/D) using synchrotron radiation phase-contrast imaging (PCI), and the relation between R/D and cell infiltration, in a model of Acute Respiratory Distress Syndrome in 6 anaesthetized and mechanically ventilated New-Zealand White rabbits. Dynamic PCI was performed at 22.6 µm voxel size, under protective mechanical ventilation [tidal volume: 6 ml/kg; positive end-expiratory pressure (PEEP): 5 cmH
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.