Evidence map›Paper›PMID 33608442›Full record

ArticleEuropean journal of hospital pharmacy : science and practice2021

Statin-induced autoimmune myopathy: a case report.

Natalia Alzueta, Marta Marin, Marta Castresana, Ana Gascón, María Pío, María Jesús Iguzquiza

Open access · greenAbstract readCase Reports
In one paragraph

Article in European journal of hospital pharmacy : science and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia AlzuetaPharmacy Management Service. Navarre Health Service, Pamplona, Spain nalzueti@navarra.es.ORCID 0000-0002-8513-239X
Marta MarinPharmacy. Navarre Health Service, Hospital Reina Sofia, Tudela, Spain.ORCID 0000-0002-0609-6467
Marta CastresanaPharmacy. Navarre Health Service, Hospital Reina Sofia, Tudela, Spain.
Ana GascónPharmacy. Navarre Health Service, Hospital Reina Sofia, Tudela, Spain.
María PíoPharmacy. Navarre Health Service, Hospital Reina Sofia, Tudela, Spain.
María Jesús IguzquizaInternal Medicine. Navarre Health Service, Hospital Reina Sofia, Tudela, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statins are widely used in the treatment of hypercholesterolemia. Muscle weakness and elevated creatine kinase (CK) are frequent side effects of statins with an incidence of about 15%. Statin-associated myopathy is more common in people who receive multiple drugs, the elderly or women but the mechanism underlying it is still unclear. These symptoms generally improve after drug discontinuation. However, there is a type of autoimmune mediated myopathy characterised by the persistence of muscle weakness and CK elevation after stopping statins. Herein, we discuss a case of autoimmune myopathy associated with statin exposure and responsive to immunossupresive drugs. The increased use of statins in recent years raises the importance of acquaintance with this disease in clinical practice.

Indexed as

Autoimmune DiseasesHydroxymethylglutaryl-CoA Reductase InhibitorsMuscular DiseasesAgedAutoantibodiesFemaleHumansAutoantibodiesHydroxymethylglutaryl-CoA Reductase Inhibitorsadverse effectanti-HMGCR antibodiesimmune-mediated necrotising myopathymyopathystatin

Identifiers

PMID33608442
PMCPMC7907700
OpenAlexW2987267216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.