Evidence map›Paper›PMID 33608426›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Prospective, Single-Arm Trial Evaluating Changes in Uptake Patterns on Prostate-Specific Membrane Antigen-Targeted

Katherine A Zukotynski, Urban Emmenegger, Sebastien Hotte, Anil Kapoor, Wei Fu, Amanda L Blackford, John Valliant, François Bénard, Chun K Kim, Mark C Markowski and 9 more

Open access · bronzeAbstract readMulticenter StudyClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Correlation of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  10. Observational
  11. Prostate-Specific Membrane Antigen-Targeted Imaging and Its Correlation with HOXB13 Expression.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  12. Article
  13. Article
  14. Bench to Bedside Development of [Molecules (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Quantitative [Scientific reports · 2023
    Article
  17. Article
  18. Non-invasive PD-L1 quantification using [Journal for immunotherapy of cancer · 2023
    Article
  19. The significance of metabolic response to neoadjuvant androgen deprivation therapy detected with [European journal of nuclear medicine and molecular imaging · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Katherine A Zukotynski
Urban EmmeneggerSunnybrook Odette Cancer Centre and Research Institute, University of Toronto, Toronto, Ontario, Canada.
Sebastien HotteDepartment of Oncology, McMaster University, Hamilton, Ontario, Canada.
Anil KapoorDepartment of Urology, McMaster University, Hamilton, Ontario, Canada.
Wei FuDivision of Biostatistics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Amanda L BlackfordDivision of Biostatistics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
John ValliantDepartment of Chemistry, McMaster University, Hamilton, Ontario, Canada.
François BénardDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.
Chun K KimDepartment of Medicine, Hanyang University College of Medicine, Seoul, South Korea.
Mark C MarkowskiSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Mario A EisenbergerSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Emmanuel S AntonarakisSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Kenneth J PientaJames Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Michael A Gorin
Matthew LubanovicDepartments of Radiology and Medicine, McMaster University, Hamilton, Ontario, Canada.
Jihyun KimDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; and.
Martin G Pomper
Steve Y ChoDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; and.
Steven P Rowe
Johns Hopkins University · USMcMaster University · CASidney Kimmel Comprehensive Cancer Center · USUniversity of Wisconsin–Madison · USHanyang University · KRSunnybrook Health Science Centre · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PET with small molecules targeting prostate-specific membrane antigen (PSMA) is being adopted as a clinical standard for prostate cancer imaging. In this study, we evaluated changes in uptake on PSMA-targeted PET in men starting abiraterone or enzalutamide.

Indexed as

AndrostenesAntigens, SurfaceBenzamidesGlutamate Carboxypeptidase IILysineNitrilesPhenylthiohydantoinPositron Emission Tomography Computed TomographyProstatic Neoplasms, Castration-ResistantAgedAged, 80 and overBiological TransportHumansMaleMiddle AgedProspective Studies2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acidabirateroneAndrostenesAntigens, SurfaceBenzamidesenzalutamideFOLH1 protein, humanGlutamate Carboxypeptidase IILysineNitrilesPhenylthiohydantoinUreaantiandrogenCRPCprognosisradiopharmaceuticalresponse assessment

Identifiers

PMID33608426
PMCPMC8724901
OpenAlexW3131780647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.