Evidence map›Paper›PMID 33608385›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Changes in Presynaptic Gene Expression during Homeostatic Compensation at a Central Synapse.

Evan R Harrell, Diogo Pimentel, Gero Miesenböck

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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  6. Transcriptional Dysregulation and Impaired Neuronal Activity inInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Evan R HarrellCentre for Neural Circuits and Behaviour, University of Oxford, Oxford OX1 3SR, United Kingdom evan-richard.harrell@pasteur.fr gero.miesenboeck@cncb.ox.ac.uk.ORCID 0000-0002-4376-9405
Diogo PimentelCentre for Neural Circuits and Behaviour, University of Oxford, Oxford OX1 3SR, United Kingdom.
Gero MiesenböckCentre for Neural Circuits and Behaviour, University of Oxford, Oxford OX1 3SR, United Kingdom evan-richard.harrell@pasteur.fr gero.miesenboeck@cncb.ox.ac.uk.
University of Oxford · GB

Funding

Medical Research Council G0700888Medical Research Council G0701225Wellcome TrustWellcome Trust 089270/Z/09/ZWellcome Trust 090309/Z/09/ZWellcome Trust 106988/Z/15/ZWellcome Trust 209235/Z/17/Z
6 · The paper itself

Abstract

Homeostatic matching of pre- and postsynaptic function has been observed in many species and neural structures, but whether transcriptional changes contribute to this form of trans-synaptic coordination remains unknown. To identify genes whose expression is altered in presynaptic neurons as a result of perturbing postsynaptic excitability, we applied a transcriptomics-friendly, temperature-inducible Kir2.1-based activity clamp at the first synaptic relay of the

Indexed as

AnimalsAnimals, Genetically ModifiedArthropod AntennaeDrosophilaFemaleGene ExpressionHomeostasisNeuronal PlasticityPresynaptic TerminalsSynapsesgene expressionhomeostatic plasticitysynaptic reorganizationsynaptic transmissiontranscriptomicstrans-synaptic signaling

Identifiers

PMID33608385
PMCPMC8026347
OpenAlexW3132801442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.