SynthesisRadiation oncology (London, England)2021
Clinical features, treatment and outcomes in patients with tracheal adenoid cystic carcinoma: a systematic literature review.
Synthesis in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- [Extracorporeal Membrane Oxygenation in Complex Tracheobronchial Surgery: A Series Case Reports and Systematic Review].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2024Pooled it
- Isolated Subcarinal Lymph Node Recurrence 24 Years After Treatment for Primary Tracheal Adenoid Cystic Carcinoma.Respirology case reports · 2026Article
- Crico-tracheal resection and anastomosis for primary and secondary tumours of the laryngo-tracheal junction: a single centre series of 78 patients.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026Article
- Thoracoscopic-assisted right thoracic approach for resection of proximal left main bronchial adenoid cystic carcinoma.Journal of cardiothoracic surgery · 2026Article
- Surgical Outcomes of Central Airway Adenoid Cystic Carcinoma: A Retrospective Single-Center Analysis.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- Case Report: Long-term survival of adenoid cystic carcinoma with central airway stenosis treated by bronchoscopic ablation combined with para-toluenesulfonamide injection.Frontiers in oncology · 2026Article
- Photodynamic therapy with local-targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12-year survival: A case report.Oncology letters · 2026Article
- Tracheobronchial adenoid cystic carcinoma: a two-center retrospective analysis of clinical features and survival outcomes.European journal of medical research · 2025Article
- Deciphering the potential pathogeny of rare tracheal adenoid cystic carcinoma by single-cell RNA-sequencing.Translational lung cancer research · 2025Article
- Chronic Cough Caused by Adenoid Cystic Carcinoma.Respirology case reports · 2025Article
- Diagnosis and Treatment of Primary Tracheobronchial Tumors.Cancer medicine · 2025Review
- Clinical Characteristics, Treatment and Prognosis of Primary Tracheal Adenoid Cystic Carcinoma: A Multicenter Retrospective Study.Cancer medicine · 2025Article
- Bronchoscopic intervention in the management of primary tracheobronchial adenoid cystic carcinoma with dyspnea.Frontiers in oncology · 2025Article
- Treatment and Outcomes of Primary Tracheal Adenoid Cystic Carcinoma: A Systematic Review.Cancer management and research · 2025Review
- Primary tracheo-bronchial adenoid cystic carcinoma: A surgical series with literature review.Respirology case reports · 2025Article
- Efficacy of Online Adaptive Radiotherapy Using Surface Guidance in Treatment of Tracheal Adenoid Cystic Carcinoma.Cureus · 2024Article
- Treatment outcomes of patients with primary tracheal tumors - analysis of a large retrospective series.BMC cancer · 2024Article
- Endotracheal enucleation and para-toluenesulfonamide injection for adenoid cystic carcinoma in the upper trachea: A novel therapeutic approach.Thoracic cancer · 2024Article
- Pulmonary adenoid cystic carcinoma - a spectrum of disease: two case reports.Respirology case reports · 2024Article
- Adenoid Cystic Carcinoma of the Minor Salivary Glands: A Systematic Review and Meta-Analysis of Clinical Characteristics and Management Strategies.Journal of clinical medicine · 2024Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPrimary tracheal adenoid cystic carcinoma (TACC) is rare and originates from the minor salivary gland. Biologically, TACC results in delayed presentation, and the therapeutic effects of multimodal treatment differ across individuals. This study aimed to review cases of TACC to identify clinical features, imaging modalities, treatment, and patient outcomes across follow-ups.
methodsThe PubMed, Web of Science and MEDLINE databases were searched to identify articles reporting cases of TACC. The study variables included in the analysis were patient demographics, biological characteristics, presenting symptoms, imaging modalities, treatments, follow-up times and survival outcomes.
resultsA total of 76 articles and 1252 cases were included in this review. The most common presenting symptom was dyspnoea (86.0%), followed by cough (58.0%). Surgery alone (40.9%), surgery with postoperative radiotherapy (36.4%) and radiotherapy alone (19.2%) were used most frequently treatments modalities. Of the 1129 cases with disease control and survival data, there was no evidence of disease in 78.7%, local recurrence was reported in 3.8%. Distant metastasis rate was 24.9% of 418 reported cases, lung (44.2%) was the most commonly involved organ. The 5, 10 years survival rate of patients treated with surgery alone and surgery with postoperative radiotherapy were 86.4%, 55.6% and 97.3%, 44.4%, respectively.
conclusionTACC most common presenting symptoms were dyspnoea, cough and shortness of breath. Surgery alone and surgery with postoperative radiotherapy are predominant treatment modalities. Both seems to provide a good result in term of disease control and long-term survival rate in patients with TACC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.