ArticleBMC microbiology2021
Potential of bacteriophages as disinfectants to control of Staphylococcus aureus biofilms.
Article in BMC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Efficacy of phage therapy in controlling staphylococcal biofilms: a systematic review.European journal of medical research · 2025Pooled it
- Isolation, genomic characterization, and biocontrol potential of a bacteriophage cocktail against Staphylococcus aureus in milk.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Characterization and complete genomic sequence of a novel phage BUCT805 infectingMicrobiology spectrum · 2026Article
- Isolation and characterization of a lytic bacteriophage against Staphylococcus aureus.BMC veterinary research · 2026Article
- Effect of temperate phage SapYZUs891 as a biocontrol agent on the Chinese foodborne multidrug-resistant Staphylococcus aureus isolates.Archives of microbiology · 2026Article
- Bacteriophage-Based Control of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2026Article
- Virus Enhanced Microrobots for Biofilm Eradication.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Preparation and pharmacokinetic evaluation of Staphylococcus phage COP-80B for treatment of periprosthetic joint infections in a mouse model.Virus research · 2025Article
- The Role of Active Packaging in the Defense Against Foodborne Pathogens with Particular Attention to Bacteriophages.Microorganisms · 2025Review
- Use of bacteriophages for biocontrol of pathogens in food and food-contact surfaces: a systematic review of the literature.Sustainable microbiology · 2025Review
- Isolation and characterization of methicillin-resistantFrontiers in microbiology · 2025Article
- Isolation and characterisation of a novel Silviavirus bacteriophage promising antimicrobial agent against methicillin-resistant Staphylococcus aureus infections.Scientific reports · 2024Article
- Emerging Approaches for Mitigating Biofilm-Formation-Associated Infections in Farm, Wild, and Companion Animals.Pathogens (Basel, Switzerland) · 2024Review
- Effective elimination of bacteria on hard surfaces by the combined use of bacteriophages and chemical disinfectants.Microbiology spectrum · 2024Article
- The current state of phage therapy in livestock and companion animals.Journal of animal science and technology · 2024Review
- Bacteriophage Therapy to Control Bovine Mastitis: A Review.Antibiotics (Basel, Switzerland) · 2023Review
- Review
- Exploring the Benefits of Metal Ions in Phage Cocktail for the Treatment of Methicillin-ResistantInfection and drug resistance · 2022Article
- Prospects of bacteriophage collections in disinfectant applications.Veterinary world · 2022Article
- Improved bactericidal efficacy and thermostability of Staphylococcus aureus-specific bacteriophage SA3821 by repeated sodium pyrophosphate challenges.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus is the causative agent of chronic mastitis, and can form a biofilm that is difficult to completely remove once formed. Disinfectants are effective against S. aureus, but their activity is easily affected by environmental factors and they are corrosive to equipment and chemically toxic to livestock and humans. Therefore, we investigated the potential utility of a bacteriophage as a narrow-spectrum disinfectant against biofilms formed by S. aureus. In this study, we isolated and characterized bacteriophage vB_SauM_SDQ (abbreviated to SDQ) to determine its efficacy in removing S. aureus biofilms.
resultsSDQ belongs to the family Myoviridae and consists of a hexagonal head, long neck, and short tail. This phage can sterilize a 10
conclusionsOur results suggest that SDQ, a specific lytic S. aureus phage, can be used to control biofilm infections. SDQ maintains its full activity in the presence of nonionic detergents, tap water, metal chelators, and organic materials, and can be used in combination with detergents. We propose this phage as a narrow-spectrum disinfectant against S. aureus, to augment or supplement the use of broad-spectrum disinfectants in the prevention and control of the mastitis and dairy industry contamination caused by S. aureus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.