Evidence map›Paper›PMID 33607607›Full record

ArticleSchizophrenia research2021

The clinical relevance of gray matter atrophy and microstructural brain changes across the psychosis continuum.

Faith M Hanlon, Andrew B Dodd, Josef M Ling, Nicholas A Shaff, David D Stephenson, Juan R Bustillo, Shannon F Stromberg, Denise S Lin, Sephira G Ryman, Andrew R Mayer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Schizophrenia research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Faith M HanlonThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA.
Andrew B DoddThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA.
Josef M LingThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA.
Nicholas A ShaffThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA.
David D StephensonThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA.
Juan R BustilloDepartment of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
Shannon F StrombergPsychiatry and Behavioral Health Clinical Program, Presbyterian Healthcare System, Albuquerque, NM 87112, USA.
Denise S LinDepartment of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
Sephira G RymanThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA.
Andrew R MayerThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA; Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA; Department of Psychology, University of New Mexico, Albuquerque, NM 87131, USA; Department of Neurology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA. Electronic address: amayer@mrn.org.
Mind Research Network · USUniversity of New Mexico · USPresbyterian Healthcare Services · US

Funding

A Multidimensional Investigation of Cognitive Control Deficits in PsychopathologyR01MH101512 · NIMH · THE MIND RESEARCH NETWORK · PI MAYER, ANDREW ROBERT · 2014 to 2017
$2.8M
NIMH NIH HHS R01 MH101512
6 · The paper itself

Abstract

Patients with psychotic spectrum disorders (PSD) exhibit similar patterns of atrophy and microstructural changes that may be associated with common symptomatology (e.g., symptom burden and/or cognitive impairment). Gray matter concentration values (proxy for atrophy), fractional anisotropy (FA), mean diffusivity (MD), intracellular neurite density (V

Indexed as

Psychotic DisordersWhite MatterAtrophyBrainGray MatterHumansBiomarkersDiffusion tensor imagingGray matter concentrationNeurite orientation dispersion and density imagingPsychotic spectrum disordersResearch domain criteria (RDoC)

Identifiers

PMID33607607
PMCPMC8137524
OpenAlexW3131819039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.