Evidence map›Paper›PMID 33607268›Full record

ReviewMolecular and cellular endocrinology2021

11β-hydroxysteroid dehydrogenases: A growing multi-tasking family.

Elise P Gomez-Sanchez, Celso E Gomez-Sanchez

Open access · greenAbstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Context-dependent roles of 11β-HSD1 in bone and skeletal muscle diseases.American journal of translational research · 2026
    Review
  3. Article
  4. The role of the mineralocorticoid receptor in skin.Molecular and cellular endocrinology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Altered Steroidome in Women with Multiple Sclerosis.International journal of molecular sciences · 2024
    Article
  11. Article
  12. Review
  13. Steroidomics in Men with Schizophrenia.International journal of molecular sciences · 2024
    Article
  14. Review
  15. Review
  16. C11-hydroxy and C11-oxo CInternational journal of molecular sciences · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. The Roles of Androgens in Humans: Biology, Metabolic Regulation and Health.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elise P Gomez-SanchezDepartment of Pharmacology and Toxicology, Jackson, MS, USA. Electronic address: egomez-sanchez@umc.edu.
Celso E Gomez-SanchezDepartment of Pharmacology and Toxicology, Jackson, MS, USA; Medicine (Endocrinology), Jackson, MS, USA; University of Mississippi Medical Center and G.V. (Sonny) Montgomery VA Medical Center(3), Jackson, MS, USA.
Jackson Memorial Hospital · US

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI GOMEZ-SANCHEZ, CELSO ENRIQUE · 2016 to 2025
$38.2M
Adrenal cell ATP1A1 mutations and mechanisms of aldosterone biosynthesisR01HL144847 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI GOMEZ-SANCHEZ, CELSO ENRIQUE · 2019 to 2022
$1.3M
Regulation of Mineralocorticoid Receptor ActionI01BX004681 · VA · G V SONNY MONTGOMERY VA MEDCIAL CENTER · PI GOMEZ-SANCHEZ, CELSO ENRIQUE · 2021 to 2023
–
BLRD VA I01 BX004681NHLBI NIH HHS R01 HL144847NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

This review briefly addresses the history of the discovery and elucidation of the three cloned 11β-hydroxysteroid dehydrogenase (11βHSD) enzymes in the human, 11βHSD1, 11βHSD2 and 11βHSD3, an NADP

Indexed as

11-beta-Hydroxysteroid DehydrogenasesAnimalsCytokinesEnzyme InhibitorsHumansReproductionTranscription, Genetic11-beta-Hydroxysteroid DehydrogenasesCytokinesEnzyme Inhibitors11β-hydroxysteroid dehydrogenase7-Keto sterolGlucocorticoidMineralocorticoidRetinoid-related orphan receptor

Identifiers

PMID33607268
PMCPMC8108011
OpenAlexW3131395202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.