ArticleKidney international2021
The time of onset of intradialytic hypotension during a hemodialysis session associates with clinical parameters and mortality.
Article in Kidney international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- A randomized controlled trial of two dialysate sodium concentrations in hospitalized hemodialysis patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022Trial
- Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence.Journal of clinical apheresis · 2026Article
- Identification of intradialytic hemodynamic phenotypes using latent profile analysis.Clinical kidney journal · 2026Article
- Physiologically-Guided Ultrafiltration: A Proposed Ultrasound Framework for Individualized Volume Removal During Hemodialysis.Nephrology (Carlton, Vic.) · 2026Review
- Review
- Article
- The value of pleth variability index in predicting hypotension during maintenance hemodialysis: a prospective observational multicenter study (PVi-HD study).BMC nephrology · 2026Observational
- Effects of Pre-Dialysis Fluid Overload, Intradialytic Relative Blood Volume Levels, and Cumulative Ultrafiltration Volume on Pulse Wave-Derived Features during Hemodialysis: Results from a Longitudinal Cohort Study.Kidney & blood pressure research · 2026Article
- Machine Learning-Based Prediction of Life-Threatening Complications During Hemodialysis in Hospitalized Patients With Poor General Conditions.Artificial organs · 2026Article
- Intra-Session recurrence in intradialytic hypotension prediction: evaluation implications and recurrence-aware modeling.Frontiers in digital health · 2026Article
- Updates in the management of intradialytic hypotension: Emerging strategies and innovations.World journal of nephrology · 2025Review
- Continuous measurement of pulse arrival time for identification of blood pressure changes in patients undergoing hemodialysis-a feasibility study.Clinical kidney journal · 2025Article
- The BestShape artificial intelligence system for real-time prediction of intradialytic hypotension-clinical outcomes after four-year follow-up.Clinical kidney journal · 2025Article
- Patterns in Heart Rate Variability during Hemodialysis.Kidney360 · 2025Article
- Prognostic Significance of Visit-to-Visit Ultrafiltration Volume Variability in Hemodialysis Patients.Biomedicines · 2025Article
- Research on the development of an intelligent prediction model for blood pressure variability during hemodialysis.BMC nephrology · 2025Article
- Knowledge, Attitudes and Practices Toward Hypotension During Hemodialysis Among Nephrology and Hemodialysis Medical Staff: A Multi-Center Cross-Sectional Study.Journal of multidisciplinary healthcare · 2025Article
- Construction and application of machine learning models for predicting intradialytic hypotension.PloS one · 2025Article
- Observational
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6 authors.
Funding
Abstract
Intradialytic hypotension (IDH) is a common complication of hemodialysis, but there is no data about the time of onset during treatment. Here we describe the incidence of IDH throughout hemodialysis and associations of time of hypotension with clinical parameters and survival by analyzing data from 21 dialysis clinics in the United States to include 785682 treatments from 4348 patients. IDH was defined as a systolic blood pressure of 90 mmHg or under while IDH incidence was calculated in 30-minute intervals throughout the hemodialysis session. Associations of time of IDH with clinical and treatment parameters were explored using logistic regression and with survival using Cox-regression. Sensitivity analysis considered further IDH definitions. IDH occurred in 12% of sessions at a median time interval of 120-149 minutes. There was no notable change in IDH incidence across hemodialysis intervals (range: 2.6-3.2 episodes per 100 session-intervals). Relative blood volume and ultrafiltration volume did not notably associate with IDH in the first 90 minutes but did thereafter. Associations between central venous but not arterial oxygen saturation and IDH were present throughout hemodialysis. Patients prone to IDH early as compared to late in a session had worse survival. Sensitivity analyses suggested IDH definition affects time of onset but other analyses were comparable. Thus, our study highlights the incidence of IDH during the early part of hemodialysis which, when compared to later episodes, associates with clinical parameters and mortality.
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