Evidence map›Paper›PMID 33607029›Full record

ArticleThe Lancet. Global health2021

Household finished flooring and soil-transmitted helminth and Giardia infections among children in rural Bangladesh and Kenya: a prospective cohort study.

Jade Benjamin-Chung, Yoshika S Crider, Andrew Mertens, Ayse Ercumen, Amy J Pickering, Audrie Lin, Lauren Steinbaum, Jenna Swarthout, Mahbubur Rahman, Sarker M Parvez and 7 more

Open access · goldAbstract read
In one paragraph

Article in The Lancet. Global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

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  9. Associations between floor material andbioRxiv : the preprint server for biology · 2025
    Article
  10. Evaluating the survival and removal ofApplied and environmental microbiology · 2025
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  16. Assemblages and Subassemblages ofJournal of parasitology research · 2024
    Article
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  19. Producing ratio measures of effect with quantitative microbial risk assessment.Risk analysis : an official publication of the Society for Risk Analysis · 2023
    Article
  20. Giardia Detection and Codetection With Other Enteric Pathogens in Young Children in the Vaccine Impact on Diarrhea in Africa (VIDA) Case-Control Study: 2015-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 3 countries.

Jade Benjamin-ChungDivision of Epidemiology & Biostatistics, University of California, Berkeley, Berkeley, CA, USA. Electronic address: jadebc@berkeley.edu.
Yoshika S CriderDivision of Epidemiology & Biostatistics, University of California, Berkeley, Berkeley, CA, USA; Energy & Resources Group, University of California, Berkeley, Berkeley, CA, USA.
Andrew MertensDivision of Epidemiology & Biostatistics, University of California, Berkeley, Berkeley, CA, USA.
Ayse ErcumenDepartment of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC, USA.
Amy J PickeringCivil and Environmental Engineering, Tufts University, Medford, MA, USA.
Audrie LinDivision of Epidemiology & Biostatistics, University of California, Berkeley, Berkeley, CA, USA.
Lauren SteinbaumExponent, Sacramento, CA, USA.
Jenna SwarthoutCivil and Environmental Engineering, Tufts University, Medford, MA, USA.
Mahbubur RahmanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Sarker M ParvezInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Rashidul HaqueInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Sammy M NjengaEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute, Nairobi, Kenya.
Jimmy KiharaEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute, Nairobi, Kenya.
Clair NullCenter for International Policy Research and Evaluation, Mathematica Policy Research, Washington, DC, USA.
Stephen P LubyDivision of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA.
John M ColfordDivision of Epidemiology & Biostatistics, University of California, Berkeley, Berkeley, CA, USA.
Benjamin F ArnoldFrancis I Proctor Foundation, University of California, San Francisco, CA, USA; Department of Ophthalmology, University of California, San Francisco, CA, USA.
University of California, Berkeley · USInternational Centre for Diarrhoeal Disease Research · BDKenya Medical Research Institute · KETufts University · USCenter for International Policy · USExponent (United States) · USNorth Carolina State University · USStanford University · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSoil-transmitted helminths and Giardia duodenalis are responsible for a large burden of disease globally. In low-resource settings, household finished floors (eg, concrete floors) might reduce transmission of soil-transmitted helminths and G duodenalis.

methodsIn a prospective cohort of children nested within two randomised trials in rural Bangladesh and Kenya, we estimated associations between household finished flooring and soil-transmitted helminths and G duodenalis prevalence. In 2015-16, we collected stool samples from children aged 2-16 years in rural Bangladesh and Kenya. We detected soil-transmitted helminth infection using quantitative PCR (qPCR; Bangladesh n=2800; Kenya n=3094), and G duodenalis using qPCR in Bangladesh (n=6894) and ELISA in Kenya (n=8899). We estimated adjusted prevalence ratios (aPRs) using log-linear models adjusted for potential confounders.

findings7187 (92·2%) of 7795 children in Bangladesh and 9077 (93·7%) of 9686 children in Kenya provided stool specimens that were analysed by qPCR. At enrolment, 691 (10%) households in Bangladesh and 471 (5%) households in Kenya had finished floors. In both countries, household finished flooring was associated with lower Ascaris lumbricoides prevalence (Bangladesh aPR 0·33, 95% CI 0·14-0·78; Kenya 0·62, 0·39-0·98) and any soil-transmitted helminths (Bangladesh 0·73, 0·52-1·01; Kenya 0·57, 0·37-0·88). Household finished floors were also associated with lower Necator americanus prevalence in Bangladesh (0·52, 0·29-0·94) and G duodenalis prevalence in both countries (Bangladesh 0·78, 0·64-0·95; Kenya 0·82, 0·70-0·97).

interpretationIn low-resource settings, living in households with finished floors over a 2-year period was associated with lower prevalence of G duodenalis and some soil-transmitted helminths in children.

fundingBill & Melinda Gates Foundation and Task Force for Global Health.

Indexed as

Rural PopulationAdolescentBangladeshChildChild, PreschoolDeveloping CountriesEnzyme-Linked Immunosorbent AssayFecesFemaleFloors and FloorcoveringsGiardiasisHelminthiasisHousingHumansKenyaMaleSoil

Identifiers

PMID33607029
PMCPMC7900607
OpenAlexW3037249771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.