ArticleJournal of experimental botany2021
Dynamic histone acetylation in floral volatile synthesis and emission in petunia flowers.
Article in Journal of experimental botany, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 42 citations in OpenAlex.
- Stable Transgenerational Epimutants in Okra Induced by Sodium Butyrate: A Novel Pathway to Functional Breeding.Biochemical genetics · 2026Article
- Integrating stress responses and secondary metabolism: the regulatory functions of histone deacetylases in medicinal plants.Frontiers in plant science · 2026Review
- Differential epigenetic regulation by blue and UV-A light reveals the key role of CsSDG36-mediated H3K4 methylation in leaf development and secondary metabolism in Camellia sinensis.Genome biology · 2025Article
- Histone deacetylases repress the accumulation of licochalcone A by inhibiting the expression of flavonoid biosynthetic pathway-related genes in licorice (Glycyrrhiza inflata).Molecular horticulture · 2025Article
- Petunia PHYTOCHROME INTERACTING FACTOR 4/5 transcriptionally activates key regulators of floral scent.Plant molecular biology · 2024Article
- The R2R3-MYB transcription factor EVER controls the emission of petunia floral volatiles by regulating epicuticular wax biosynthesis in the petal epidermis.The Plant cell · 2023Article
- Organ-specific characteristics govern the relationship between histone code dynamics and transcriptional reprogramming during nitrogen response in tomato.Communications biology · 2023Article
- Identification of histone acetyltransferase genes responsible for cannabinoid synthesis in hemp.Chinese medicine · 2023Article
- Transcriptomic and metabolomic data reveal key genes that are involved in the phenylpropanoid pathway and regulate the floral fragrance of Rhododendron fortunei.BMC plant biology · 2023Article
- Developmental and temporal changes in petunia petal transcriptome reveal scent-repressing plant-specific RING-kinase-WD40 protein.Frontiers in plant science · 2023Article
- A whiff of the future: functions of phenylalanine-derived aroma compounds and advances in their industrial production.Plant biotechnology journal · 2022Review
- Genome-Wide Identification of PetuniaInternational journal of molecular sciences · 2022Article
- ODORANT1 targets multiple metabolic networks in petunia flowers.The Plant journal : for cell and molecular biology · 2022Article
- Floral Scents and Fruit Aromas: Functions, Compositions, Biosynthesis, and Regulation.Frontiers in plant science · 2022Review
- Headspace Volatiles and Endogenous Extracts ofMolecules (Basel, Switzerland) · 2021Article
- Histone acetylation: a requirement for petunia floral scent.Journal of experimental botany · 2021Article
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Biosynthesis of secondary metabolites relies on primary metabolic pathways to provide precursors, energy, and cofactors, thus requiring coordinated regulation of primary and secondary metabolic networks. However, to date, it remains largely unknown how this coordination is achieved. Using Petunia hybrida flowers, which emit high levels of phenylpropanoid/benzenoid volatile organic compounds (VOCs), we uncovered genome-wide dynamic deposition of histone H3 lysine 9 acetylation (H3K9ac) during anthesis as an underlying mechanism to coordinate primary and secondary metabolic networks. The observed epigenome reprogramming is accompanied by transcriptional activation at gene loci involved in primary metabolic pathways that provide precursor phenylalanine, as well as secondary metabolic pathways to produce volatile compounds. We also observed transcriptional repression among genes involved in alternative phenylpropanoid branches that compete for metabolic precursors. We show that GNAT family histone acetyltransferase(s) (HATs) are required for the expression of genes involved in VOC biosynthesis and emission, by using chemical inhibitors of HATs, and by knocking down a specific HAT gene, ELP3, through transient RNAi. Together, our study supports that regulatory mechanisms at chromatin level may play an essential role in activating primary and secondary metabolic pathways to regulate VOC synthesis in petunia flowers.
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