ArticlePloS one2021
Low skeletal muscle radiodensity is the best predictor for short-term major surgical complications in gastrointestinal surgical cancer: A cohort study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- CT-derived myosteatosis as a predictor of postoperative outcomes in esophagogastric cancer surgery: a systematic review.Frontiers in medicine · 2026Pooled it
- Computed Tomography-Defined Fat Composition as a Prognostic Marker in Gastric Adenocarcinoma: A Systematic Review and Meta-Analysis.Digestive diseases (Basel, Switzerland) · 2023Pooled it
- Predictive value of preoperative handgrip strength on postoperative outcomes in patients with gastrointestinal tumors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Skeletal Muscle Gauge and Complementary Pan-Immune-Inflammation Value for Risk Stratification of 30-Day Major Complications After Colorectal Cancer Surgery.Biomedicines · 2026Article
- CT-Assessed Body Composition as Predictor of Post-Operative Complications in Lung Cancer Patients.Cancers · 2026Review
- Nomogram predicting short- and long-term outcomes in colon cancer based on CT body composition.International journal of colorectal disease · 2025Article
- A potential bioelectrical impedance equation for estimating skeletal muscle area using computed tomography in colorectal cancer.Scientific reports · 2025Article
- Article
- Sarcopenia as a Prognostic Factor for the Outcomes of Surgical Treatment of Colorectal Carcinoma.Healthcare (Basel, Switzerland) · 2025Review
- Sex-specific CT-derived muscle and fat phenotypes in colon cancer: implications for nutritional and metabolic assessment.Frontiers in nutrition · 2025Article
- Impact of body composition and muscle health phenotypes on survival outcomes in colorectal cancer: a multicenter cohort.Scientific reports · 2024Article
- Influence of Body Composition Assessed by Computed Tomography on Mortality Risk in Young Women with Breast Cancer.Nutrients · 2024Article
- Thigh muscle by CT images as a predictor of mortality in patients with newly diagnosed colorectal cancer.Scientific reports · 2024Article
- Age-adjusted Charlson comorbidity index and its association with body composition and overall survival in patients with colorectal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Examining variations in body composition among patients with colorectal cancer according to site and disease stage.Scientific reports · 2024Article
- Sarcopenia assessed by total psoas index - is it correlated with post-operative complications in all digestive cancers?Medicine and pharmacy reports · 2023Article
- Relationship between circulating tumour DNA and skeletal muscle stores at diagnosis of pancreatic ductal adenocarcinoma: a cross-sectional study.Scientific reports · 2023Article
- Preoperative low absolute and relative handgrip strength as predictors of postoperative short-term outcomes: a prospective study based on patients aged 60 years and older with gastric cancer.European geriatric medicine · 2023Observational
- The Impact of Body Mass Composition on Outcome in Multiple Traumatized Patients-Results from the Fourth Thoracic and Third Lumbar Vertebrae: A Single-Center Retrospective Observational Study.Journal of clinical medicine · 2023Article
- Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient.JPEN. Journal of parenteral and enteral nutrition · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate whether body composition, muscle function, and their association are predictive factors for short-term postoperative complications in patients with gastric and colorectal cancer. A prospective cohort study was conducted with patients undergoing resection of gastric and colorectal tumors. Nutritional status was assessed using Patient-Generated Subjective Global Assessment (PG-SGA) and anthropometric techniques. Low handgrip strength (HGS) was observed when <16kg for women, and <27kg for men. Computed tomography images were used to measure visceral adipose tissue, skeletal muscle index (SMI), and skeletal muscle radiodensity (SMD). Complications of grade II or above (according to Clavien-Dindo's classification) were considered in a follow-up period of up to 30 days after surgery. Major complications were defined when they reached grade III or above. A total of 84 patients were analyzed (57.1% female, 59.7 ± 12.6 years) and 19% were diagnosed with low HGS + low SMI or SMD. Postoperative complications occurred in 51.2%, and these patients presented significantly longer duration of surgery and hospital stay. Major complications were observed in 16.7% of the total number of patients. Binary logistic regression adjusted by age, sex, and tumor staging showed that low SMD, low HGS + low SMI or SMD, and obesity were independent risk factors for postoperative complications, but only low SMD was an independent risk factor for major postoperative complications. Low SMD is an independent risk factor for short-term major complications following surgery in patients with gastric and colorectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.