Evidence map›Paper›PMID 33606711›Full record

Observational studyPloS one2021

Features of patients that died for COVID-19 in a hospital in the south of Mexico: A observational cohort study.

Jesús Arturo Ruíz-Quiñonez, Crystell Guadalupe Guzmán-Priego, Germán Alberto Nolasco-Rosales, Carlos Alfonso Tovilla-Zarate, Oscar Israel Flores-Barrientos, Víctor Narváez-Osorio, Guadalupe Del Carmen Baeza-Flores, Thelma Beatriz Gonzalez-Castro, Carlos Ramón López-Brito, Carlos Alberto Denis-García and 2 more

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jesús Arturo Ruíz-QuiñonezSecretaría de Salud, Hospital de Alta Especialidad Dr. Juan Graham Casasús, Villahermosa, Tabasco, México.
Crystell Guadalupe Guzmán-PriegoDivisión Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, México.
Germán Alberto Nolasco-RosalesDivisión Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, México.
Carlos Alfonso Tovilla-ZarateDivisión Académica Multidisciplinaria de Comalcalco, Universidad Juárez Autónoma de Tabasco, Comalcalco, Tabasco, México.
Oscar Israel Flores-BarrientosSecretaría de Salud, Hospital de Alta Especialidad Dr. Juan Graham Casasús, Villahermosa, Tabasco, México.
Víctor Narváez-OsorioSecretaría de Salud, Hospital de Alta Especialidad Dr. Juan Graham Casasús, Villahermosa, Tabasco, México.
Guadalupe Del Carmen Baeza-FloresDivisión Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, México.
Thelma Beatriz Gonzalez-CastroDivisión Académica de Multidisciplinaria de Jalpa de Méndez, Universidad Juárez Autónoma de Tabasco, Jalpa de Méndez, Tabasco, México.
Carlos Ramón López-BritoSecretaría de Salud, Hospital de Alta Especialidad Dr. Juan Graham Casasús, Villahermosa, Tabasco, México.
Carlos Alberto Denis-GarcíaSecretaría de Salud, Hospital de Alta Especialidad Dr. Juan Graham Casasús, Villahermosa, Tabasco, México.
Agustín Pérez-GarcíaSecretaría de Salud, Hospital de Alta Especialidad Dr. Juan Graham Casasús, Villahermosa, Tabasco, México.
Isela Esther Juárez-RojopDivisión Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, México.ORCID 0000-0003-3760-7394

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the wide spread of SARS-CoV2 around the world, the risk of death in individuals with metabolic comorbidities has dangerously increased. Mexico has a high number of infected individuals and deaths by COVID-19 as well as an important burden of metabolic diseases; nevertheless, reports about features of Mexican individuals with COVID-19 are scarce. The aim of this study was to evaluate demographic features, clinical characteristics and the pharmacological treatment of individuals who died by COVID-19 in the south of Mexico.

methodsWe performed an observational study including the information of 185 deceased individuals with confirmed diagnoses of COVID-19. Data were retrieved from medical records. Categorical data were expressed as proportions (%) and numerical data were expressed as mean ± standard deviation. Comorbidities and overlapping symptoms were plotted as Venn diagrams. Drug clusters were plotted as dendrograms.

resultsThe mean age was 59.53 years. There was a male predominance (60.1%). The mean hospital stay was 4.75 ± 4.43 days. The most frequent symptoms were dyspnea (88.77%), fever (71.42%) and dry cough (64.28%). Present comorbidities included diabetes (60.63%), hypertension (59.57%) and obesity (43.61%). The main drugs used for treating COVID-19 were azithromycin (60.6%), hydroxychloroquine (53.0%) and oseltamivir (27.3%).

conclusionsMexican individuals who died of COVID-19 had shorter hospital stays, higher frequency of shortness of breath, and higher prevalence of diabetes than individuals from other countries. Also, there was a high frequency of off-label use of drugs for their treatment.

Indexed as

COVID-19 Drug TreatmentDiabetes Mellitus, Type 1Hospital MortalityObesitySARS-CoV-2AdultAgedAzithromycinCOVID-19FemaleHospitalsHumansHydroxychloroquineLength of StayMaleMexicoAzithromycinHydroxychloroquineOseltamivir

Identifiers

PMID33606711
PMCPMC7894952

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.